A Review: The Location, Molecular Characterization and Multipotency of Hair Follicle Epidermal Stem Cells

    November 2004 in “ Annals of the Academy of Medicine Singapore ”
    Dongrui Ma, EN Yang, ST Lee
    Studysummary This review examines the location and markers of hair follicle stem cells, finding that they are primarily located in the bulge region and can contribute to various skin structures, but challenges remain in distinguishing them from their progeny.
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    Research cited in this study 8

    1. Reepithelialization of a Full-Thickness Burn from Stem Cells of Hair Follicles Micrografted into a Tissue-Engineered Dermal Template (Integra) Plastic and Reconstructive Surgery · 2004
    2. Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge Journal of Investigative Dermatology · 2003
    3. Enrichment for Living Murine Keratinocytes from the Hair Follicle Bulge with the Cell Surface Marker CD34 Journal of Investigative Dermatology · 2003
    4. An Improved and Rapid Method to Construct Skin Equivalents from Human Hair Follicles and Fibroblasts Experimental dermatology · 2001
    5. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001
    6. Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis Cell · 2000
    7. Keratin 19 as a Biochemical Marker of Skin Stem Cells In Vivo and In Vitro: Localization and Variation with Age and Culture Stage Journal of Cell Science · 1996
    8. Cells Within the Bulge Region of Mouse Hair Follicle Transiently Proliferate During Early Anagen: Heterogeneity and Functional Differences of Various Hair Cycles Differentiation · 1994