New Hyaluronan-Based Biomatrix for 3D Follicle Culture Yields Functionally Competent Oocytes
July 2022
in “
Research Square (Research Square)
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hyaluronan tyramine-linked hyaluronan hydrogel follicle encapsulation in vitro follicle maturation pre-antral follicles antrums hCG trigger oocyte-cumulus complexes GVBD MII fertilization rate blastulation rate IVM oocytes metaphase II oocytes blastocyst stage HA human chorionic gonadotropin germinal vesicle breakdown in vitro maturation mature oocytes
Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.
Studysummary This study found that tyramine-linked hyaluronan gel effectively supports the 3-D culture of ovarian follicles, facilitating the maturation of functional metaphase II oocytes that can develop into blastocysts.
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