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Fibroblasts can be turned into melanocytes for potential skin treatments.

This review discusses the role of Toll-like receptors in wound healing and highlights their potential therapeutic value but notes that their role in human wound healing and chronic wounds is not well understood.

This study established a new in vitro culture system that supports the growth and dynamic self-organization of hair follicle stem cells and their progeny, promoting a stable population equilibrium.

This study demonstrates that c-MYC overexpression in sebaceous glands affects differentiation via a regulatory axis involving the androgen receptor and p53, influencing carcinoma formation outcomes.

This study found that male pattern baldness in European males is strongly heritable and associated with genetic markers linked to earlier puberty, bone density, and pancreatic function.

This study found that H-Ras activation in aged mouse skin leads to increased dysplasia and progression to in situ squamous cell carcinoma, highlighting an age-linked connection between immune changes, senescence, and cancer risk.

In this review, the researchers detailed how the p63 transcription factor influences epithelial stem cell activities such as self-renewal, differentiation, and proliferation, highlighting the role of TAp63 and ΔNp63 isoforms in both normal tissue development and cancer pathogenesis.

This review explores how sex differences influence the pathophysiology, incidence, and treatment outcomes of ischaemic heart disease, and emphasizes the need for more sex-specific research.

This study found that the vitamin D receptor is essential for the self-renewal, migration, and differentiation of epidermal stem cells during skin wound healing in mice.

This study observed that Aconiti Ciliare Tuber extract may promote hair growth in mice by activating the Wnt/β-catenin signaling pathway.

This review discusses the International Evidence-Based PCOS Guidelines, which aim to improve diagnosis and management of PCOS and its associated comorbidities, noting the importance of early intervention and healthy lifestyle changes; it reports no new results.

This study found that Hoxc gene expression can reprogram mesenchymal dermal papilla cells, enhance epithelial stem cell regenerative potential, and promote region-specific hair follicle regeneration through Wnt signaling.

This review discusses the role of epidermal differentiation complex genes and epigenetic mechanisms in skin development and certain diseases, emphasizing their potential for improving drug development and delivery systems but provides no new experimental results.

This discussion proposes a model to incorporate patients with hormone-resistant prostate cancer into the existing framework by redefining hormone resistance and exploring new therapeutic approaches.

This review discusses the role of the TCL1 transgenic mouse model in understanding chronic lymphocytic leukemia biology and highlights the importance of exploring new pathogenetic and therapeutic targets.

This review examines how fibroblasts contribute to regeneration in various organs and explores the potential of reverting adult fibroblasts to a fetal-like state for regenerative therapies, but reports no new empirical findings.

This review discusses advances in using molecular tools from skin biology to manipulate adult stem cells for regenerative medicine and reports no new clinical results.

This study found that in mouse skin, the activation of stem/progenitor cells is synchronized across different niches during growth, with the glutamate transporter SLC1A3 playing a crucial role in this process.

This review discusses the emerging roles of transit-amplifying cells in tissue regeneration and cancer formation, highlighting their significance beyond a mere transitional state in hair follicles and the hematopoietic system.

This study suggests that canonical BMP signaling, particularly involving Smad1 and Smad5, plays a critical role in hair follicle stem cell regulation and hair morphogenesis, with distinct roles from pSmad8.

This study found that thyroxine modulates peripheral molecular clock gene expression in human hair follicles, which may have implications for treating clock-related diseases in patients with thyroid dysfunction.

This article reviews the role of microRNAs as epigenetic modulators in dermatology but reports no new clinical findings.

This review discusses the potential roles of calcium in the regulation of pluripotent and tissue-specific stem cells but reports no new experimental results, highlighting areas for future research.

This review highlights that frontal fibrosing alopecia’s increasing incidence may involve immune, genetic, hormonal, and environmental factors, yet its pathogenesis remains complex and not fully understood.

This review explores recent insights into how intrinsic gene oscillations and molecular interactions in hair follicle stem cells contribute to their regenerative potential, with potential implications for regenerative medicine, but reports no new clinical results.

This review discusses the mechanisms governing epidermal stem and progenitor cell differentiation, emphasizing the balance necessary for maintaining skin barrier function, and reports no new experimental findings.

This review examines the diverse roles of SRD5α enzymes across species, focusing on their involvement in steroid synthesis, sexual development, and various physiological processes, but reports no new clinical results.

This study found that MED1 deficiency in keratinocytes accelerates skin wound healing in young mice but delays healing in older mice, suggesting differential roles in epidermal regeneration with age.

This study found that telomere shortening disrupts BMP/pSmad/P63 signaling, leading to skin atrophy via Follistatin up-regulation, and suggests potential therapeutic targets.

This study reports that dynamic interactions between stem cells and their niche, influenced by macro-environmental factors, regulate regenerative behavior in integument pattern formation.