P63: A Crucial Player In Epithelial Stemness Regulation
October 2023
in “
Oncogene
”
Research cited in this study
7 / 7 results
research P63 Targeted Deletion Under the FOXN1 Promoter Disrupts Pre- and Post-Natal Thymus Development, Function, and Maintenance, and Induces Severe Hair Loss
Deleting the p63 gene in certain cells causes problems in thymus development and severe hair loss in mice.
research Mechanism of TAp73 Inhibition by ΔNp63 and Structural Basis of p63/p73 Hetero-Tetramerization
ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.
research Interleukin 6 and STAT3 Regulate p63 Isoform Expression in Keratinocytes During Regeneration
The conclusion is that the IL-6/STAT3 activation affects p63 expression in healing wounds, which may help in hair follicle regeneration.
research Plasticity of Epithelial Stem Cells in Tissue Regeneration
Epithelial stem cells can adapt and help in tissue repair and regeneration.
research p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis
p63 controls Satb1 to help skin develop properly.
research P63 Expression Pattern During Rat Epidermis Morphogenesis and the Role of P63 as a Marker for Epidermal Stem Cells
P63 is a marker for epidermal stem cells in rats.
research Expression of Beta-Catenin, p63, and CD34 in Hair Follicles During the Course of Androgenetic Alopecia
Higher p63 and CD34 levels found in specific scalp areas may affect hair loss progression.