Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study developed a method for generating germ-like tissues called bbHFGs, which efficiently promoted hair follicle formation in mice, potentially advancing hair regenerative medicine applications.

In this study, researchers found that changes in Wnt signaling pathways play a crucial role in feather follicle morphogenesis during chicken embryo development.

This review discusses the anatomy and gene involvement in the development of animal hair follicles and reports no new experimental results; it calls for continued examination of gene roles in hair quality.

This review revisits the mechanisms of wound induced hair follicle neogenesis in mice and concludes that the process involves canonical WNT signaling activated by Fgf9 from γδ T cells, but more research is needed to fully understand its cellular bases.

This study identified 77 genes with significant expression changes in expanded human skin, suggesting possible mechanisms for skin regeneration during tissue expansion, including previously unreported genes like HOXA5, HOXB2, and AP1.

Using a transgenic pig model, this study demonstrated that LGR5 is a marker of hair follicle stem cells across different species, with important similarities and differences in gene expression and developmental processes.

This study found that extracellular factors from a specific developmental stage can promote hair follicle neogenesis in adult skin by facilitating interactions between fibroblasts and keratinocytes.

This study found that transgenic mice expressing IGF-1 in their skin showed significant skin changes, early hair follicle generation, and a higher propensity to develop tumors after chemical promotion, suggesting IGF-1's role in skin carcinogenesis.

This review discusses the progress in identifying stem cells responsible for tissue regeneration and highlights technological advances in tracking their behavior, but reports no new clinical results.

This study constructed a comprehensive atlas of prenatal human skin, revealing that innate immune cells, such as macrophages, play a crucial role in skin morphogenesis by interacting with non-immune cells, influencing hair follicle formation and angiogenesis beyond their traditional immune functions.

In this study, fingertip regeneration in mice was associated with specific signaling pathways involving hair follicles and hedgehog signaling, with potential implications for improving human hand injury treatments.

This study examined prenatal and postnatal development of rat skin, observing marked changes in epidermal thickness and collagen fiber distribution as the rats aged.

This study found that Hopx labels a long-lived progenitor population in hair follicles, which contributes to hair follicle stem cell homeostasis and has an alternative origin from previously thought progenitors.

In this study, researchers found that Notch signaling is crucial for late-stage epidermal differentiation and postnatal hair cycle homeostasis by regulating hair follicle stem cell proliferation and differentiation.

This study found that nestin-expressing progenitor cells, capable of becoming ORS keratinocytes, are present in both developing and adult mouse hair follicles.

This review discusses historical and recent advances in understanding the embryonic organizer's role in patterning during development, including molecular pathways and future research challenges, but reports no new experimental data.

This protocol describes a method for regenerating hair follicles using a bioengineering technique called the Organ Germ Method, but it reports no new clinical results.

This article discusses the use of histoculture in cancer treatment, hair growth studies, and immune response research, but reports no new clinical results.

This study describes a protocol for generating hair-bearing skin organoids from human pluripotent stem cells, achieving full complexity resembling fetal skin tissue by day 130 in vitro.

Stem cells in developing hair follicles move to specific areas as they mature.

This study suggests that Sonic hedgehog from hair follicles may support the proliferation of dentate neural stem cells in mice through transport by platelets during the perinatal period.

This study developed an in vitro model using human follicular keratinocytes to observe selective cell growth and differentiation, potentially aiding future research on hair biology and growth processes.

This review discusses the principles, methods, advantages, and limitations of lineage tracing in stem cell and developmental biology but does not report new findings.

This chapter discusses stem cell activity in feather and hair follicles, emphasizing how stem cells maintain their population by cycling between quiescence and activation in specialized niches but reports no new results.

In this study, researchers used quantitative fate mapping to investigate how the infundibulum, part of the epidermis, is maintained during adulthood, finding that progenitors maintain this tissue through stochastic cell fate choices, with cells at the bottom providing transient support during hair growth phases.

This study found that matrix progenitor cells in hair follicles move in a conveyor-belt-like fashion along the dermal papilla, changing their transcriptional states and lineage potential as they differentiate into inner hair follicle layers.

This study reports that dynamic interactions between stem cells and their niche, influenced by macro-environmental factors, regulate regenerative behavior in integument pattern formation.