research High-Resolution Mass Spectrometric Investigation of the Phase I and II Metabolites of Finasteride in Pig Plasma, Urine, and Bile
Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.
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research In Vitro Performance of Dutasteride-Nanostructured Lipid Carriers Coated with Lauric Acid-Chitosan Oligomer for Dermal Delivery
Dutasteride-loaded nanoparticles coated with Lauric Acid-Chitosan show promise for treating hair loss due to their controlled release, low toxicity, and potential to stimulate hair growth.
research Intestinal Permeability Study of Minoxidil: Assessment of Minoxidil as a High Permeability Reference Drug for Biopharmaceutics Classification
Minoxidil works well as a high permeability reference drug for biopharmaceutics classification.
research Early Onset Androgenic Alopecia as the Male Phenotypic Equivalent of Polycystic Ovarian Syndrome Is Associated with High Oxidative Stress
Men with early hair loss may have higher health risks similar to women with PCOS.
research Changes in Metabolic Profile in Women with a History of PCOS: A Long-Term Follow-Up Study
Women with PCOS are at high risk of glucose metabolism issues and heart diseases, especially if overweight, highlighting the need for early intervention.
research Genetic Diversity of Armillaria Species Symbiotic with Polyporus Umbellatus in China
Different types of Armillaria fungus have a high genetic variety when partnering with Polyporus umbellatus mushrooms in China.
research Adsorptive Cathodic Stripping Determination of Minoxidil in Pharmaceutical, Cream, and Shampoo Products
Researchers developed a sensitive method to measure minoxidil in various products with high accuracy.
research Phenolic Composition, Enzyme Inhibitory, and Antioxidant Activity of Bituminaria Bituminosa
The water extract of Bituminaria bituminosa, high in phenolic compounds, shows strong antioxidant and enzyme inhibitory potential.
research Prolonged Hypotension Induced by Ingesting a Topical Minoxidil Solution: Analysis of Minoxidil and Its Metabolites
Swallowing a lot of minoxidil, a hair growth liquid, can cause severe and long-lasting low blood pressure.
research Green Tea: Health Benefits
Green tea may help with health issues like cancer, heart disease, and weight loss due to its high catechin content.
research Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations
Method detects finasteride in plasma at very low concentrations.
research Development and Validation of a New Gas Flame Ionization Detector Method for the Determination of Finasteride in Tablets
New method accurately measures finasteride in tablets.
research Lab Quality Management and Methodology
Men with early balding should be checked for metabolic syndrome, as there's a link between the two.
research Analysis of Lipids in the Medulla of Japanese Hair and Their Function
Lipids in Japanese hair help maintain glossiness and structure.
research Transfollicular Drug Delivery: Penetration of Drugs Through Human Scalp Skin and Comparison of Penetration Between Scalp and Abdominal Skins In Vitro
Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.
research Inhibition of 3-Methylcrotonyl-CoA Carboxylase Explains the Increased Excretion of 3-Hydroxyisovaleric Acid in Valproate-Treated Patients
Valproic acid treatment increases a specific acid in urine by blocking an enzyme, possibly causing skin rash and hair loss.
research Integrated Flow Injection-Solid Phase Spectrophotometric Determination of Minoxidil
New method measures minoxidil concentration faster, more accurately, and automatically.
research Quantification of Riboflavin and Thiamine in Geographical Indication Branded Yogurts from Bogura, Bangladesh Using HPLC with a Fluorescence Detector
The conclusion is that the tested yogurts from Bangladesh are rich in vitamins thiamine and riboflavin, and the testing method is reliable.
research Announcements
A woman with lupus had hair loss and skin issues that were successfully treated with medications.
research Maternal Western Diet Causes Inflammatory Milk and TLR2/4-Dependent Neonatal Toxicity
A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.
research Evidence of the Moderating Role of Hair Cortisol and Hair Cortisone in the Relationship Between Work Stress and Depression Symptoms Among Chinese Fishermen
Hair cortisol and cortisone levels may affect how work stress influences depression in Chinese fishermen.
research Simultaneous Estimation of Minoxidil and Aminexil in Bulk and Pharmaceutical Formulations by RP-HPLC Method
A new method accurately measures minoxidil and aminexil in drugs.
research Localized Cutaneous Necrosis Associated with the Antiphospholipid Syndrome
A woman with lupus experienced skin death due to a blood clotting disorder after stopping a blood thinner, which healed with treatment.
research Simultaneous Determination of Quercitrin, Afzelin, Amentoflavone, Hinokiflavone in Rat Plasma by UFLC-MS-MS and Its Application to the Pharmacokinetics of Platycladus Orientalis Leaves Extract
Researchers developed a method to measure plant compounds in rat blood and found they are quickly absorbed and eliminated within 36 hours.
research A Fast and Efficient UPLC-ESI-MS/MS Method for Detection, Identification, and Quantitative Analysis of Bioactive Substances in Medicinal Herbal Extracts for Preventing Hair Loss
Researchers developed a quick and sensitive method to identify and measure hair growth-promoting substances in a herbal mix.
research Skin Permeability and Transdermal Delivery Route of 50-nm Indomethacin-Loaded PLGA Nanoparticles
50-nm nanoparticles are better at penetrating skin and targeting hair follicles for drug delivery than 100-nm ones.
research Development and Optimization of Spironolactone Nanoparticles for Enhanced Dissolution Rates and Stability
Nanoparticles with more oleic acid improved the delivery and stability of the drug spironolactone.
research Roxithromycin-Loaded Lipid Nanoparticles for Follicular Targeting
Tiny particles carrying roxithromycin can effectively target and deliver the drug to hair follicles without irritation.
research In Vitro Selective Inhibition of Human UDP-Glucuronosyltransferase (UGT) 1A4 by Finasteride and Prediction of In Vivo Drug–Drug Interactions
Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.
research Determination of Illegal Adulteration of Dietary Supplements with Synthetic Hair-Growth Compounds by UPLC and LC-Q-TOF/MS
The new method accurately detects illegal hair-growth drugs in dietary supplements.