Early Onset Androgenic Alopecia as the Male Phenotypic Equivalent of Polycystic Ovarian Syndrome Is Associated with High Oxidative Stress

The study explored the link between early onset androgenetic alopecia (EAGA) in 30 men and metabolic and oxidative stress parameters, comparing them to 30 healthy controls. It found that men with EAGA had lower antioxidant capacity and higher oxidative stress markers, such as malondialdehyde, along with insulin resistance and elevated homocysteine levels, suggesting increased cardiovascular risk. These findings paralleled metabolic issues seen in women with polycystic ovarian syndrome (PCOS), indicating that men with EAGA might face similar long-term health risks, including metabolic syndrome, diabetes, and cardiovascular diseases. The study called for larger studies to confirm these results, noting limitations like the small sample size.