Phenolic Composition, Enzyme Inhibitory, and Antioxidant Activity of Bituminaria Bituminosa

The study from 2016 examined the antioxidant and enzyme inhibitory properties of different extracts from Bituminaria bituminosa. The methanol extract showed the highest total antioxidant activity, while the water extract was most effective in scavenging free radicals and had the highest activity in certain antioxidant assays. The water extract also had the highest α-glucosidase inhibitory activity and phenolic content, with significant amounts of rosmarinic acid, luteolin, quercetin, and rutin. The ethyl acetate extract was most effective in inhibiting α-amylase. None of the extracts inhibited cholinesterase or tyrosinase. The study concluded that the water extract, rich in phenolic compounds, could be a potential source of new antioxidant and enzyme inhibitory agents, and that there is a strong correlation between the biological activities of the extracts and their total phenolic contents.