Development and Validation of a New Gas Flame Ionization Detector Method for the Determination of Finasteride in Tablets

    February 2006 in “ Analytical Biochemistry ”
    Serap Saglik, Sevgi Tatar Ulu
    Studysummary This study reported a simple and validated gas chromatography method to accurately measure finasteride in tablets, showing equivalency to the official method with no significant differences.
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    Research cited in this study 12

    1. Determination of Finasteride in Tablet Form by Liquid Chromatography and Its Analytical Method Validation Analytica Chimica Acta · 2006
    2. Polarographic Behavior and Determination of Finasteride Farmaco · 2003
    3. A Stability-Indicating HPLC Method to Determine Finasteride in a Tablet Formulation Journal of Liquid Chromatography & Related Technologies · 2002
    4. LC Determination of Finasteride and Its Application to Storage Stability Studies Journal of Pharmaceutical and Biomedical Analysis · 2001
    5. Determination of Finasteride in Human Plasma by Liquid-Liquid Extraction and High-Performance Liquid Chromatography Journal of Chromatography B: Biomedical Sciences and Applications · 2000
    6. Finasteride Drugs · 1999
    7. Finasteride Drugs · 1999
    8. Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations Analytical Chemistry · 1998
    9. Finasteride in Biological Fluids: Extraction and Separation by a Graphitized Carbon Black Cartridge and Quantification by High-Performance Liquid Chromatography Journal of Chromatography B: Biomedical Sciences and Applications · 1997
    10. High-Performance Liquid Chromatographic Determination of Finasteride in Human Plasma Using Direct Injection with Column Switching Journal of Chromatography B: Biomedical Sciences and Applications · 1996
    11. Synthesis of 5,6,6-[2H3]Finasteride and Quantitative Determination of Finasteride in Human Plasma at Picogram Level by an Isotope-Dilution Mass Spectrometric Method Journal of Chromatography B: Biomedical Sciences and Applications · 1995
    12. Picogram Determination of Finasteride in Human Plasma and Semen by High-Performance Liquid Chromatography with Atmospheric-Pressure Chemical-Ionization Tandem Mass Spectrometry Journal of Chromatography B: Biomedical Sciences and Applications · 1994