research The Evaluation and Treatment of Androgen Excess
High androgen levels can cause excessive hair growth and may indicate serious health issues, including heart disease and fertility problems.
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research An ERK-Dependent Molecular Switch Antagonizes Fibrosis and Promotes Regeneration in Spiny Mice
High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
research Testosterone, Sex Hormone-Binding Globulin, and Dehydroepiandrosterone Levels and Cervical Length of Egyptian Women with a History of Recurrent Miscarriages, Polycystic Ovary Syndrome, and Without the Conditions at Three Stages of Pregnancy
High DHEA and short cervical length in women with PCOS and recurrent miscarriages may harm pregnancy outcomes.
research Antioxidant and Antiproliferative Activity of Finasteride Against Glioblastoma Cells
High-dose finasteride may help treat glioblastoma but needs localized delivery for effectiveness.
research Alopecia in Preexisting Autoimmune Thyroid Disease in Family Medicine Practice: Can Hyperprolactinemia Induce Hair Loss? A Case Report
High prolactin levels might be linked to hair loss in autoimmune thyroid disease, but more research is needed.
research Subchronic Study of Sperm Morphology, Genotoxic and Mutagenic Effect of Lepidium Sativum Seeds Aqueous Extract In Vivo
High doses of Lepidium sativum seed extract are toxic and should be used with caution.
research YKL-40: A Sensitive Biomarker for Early Androgenetic Alopecia and Early Hidden Metabolic Syndrome
High YKL-40 levels predict early hair loss and hidden metabolic issues.
research Association Between Lipid Accumulation Product and Hirsutism in Patients with Polycystic Ovary Syndrome
High Lipid Accumulation Product levels are linked to more hirsutism in women with Polycystic Ovary Syndrome.
research The Effect of Different Concentrations of All-Trans Retinoic Acid on the Growth and Survival of Mouse Hair Follicle Stem Cells
High concentrations of retinoic acid kill hair follicle stem cells, while low concentrations may help treat skin diseases.
research A Case Control Study to Determine the Correlation Between Serum Ferritin Levels and Chronic Telogen Effluvium in a Tertiary Hospital, Mandya
High ferritin levels might be linked to chronic hair loss.
research Survival of Densely Packed Follicular Unit Grafts Using the Lateral Slit Technique
High-density hair transplants can have high survival rates with improved techniques, but lower densities might also give good results.
research Hard X-Ray Microscopic Images of the Human Hair
High-resolution x-ray images showed three main structures in human hair: medulla, cortex, and cuticle.
research Elevation of Serum Triglyceride and Cholesterol Levels from Isotretinoin Therapy with Concomitant Oral Contraceptives
Taking oral contraceptives while on isotretinoin may increase the risk of high triglyceride and cholesterol levels.
research 28-Day Repeated Dose Toxicity and Toxicokinetics Study on Dihydroartemisinin in SD Rats
High doses of dihydroartemisinin caused reversible liver toxicity in rats, with females more affected than males.
research Evaluation of Geh Gene Expression in Staphylococcus Aureus Isolated from Acne Patients
High Geh gene expression in Staphylococcus aureus contributes to acne.
research Leydig Cell Tumor: A Rare Cause of Post-Menopausal Hyperandrogenism
Leydig cell tumors can cause high testosterone and symptoms in postmenopausal women, and removing them improves symptoms.
research Uric Acid in a Male's Life
High uric acid can cause health issues, so managing it with lifestyle changes is important.
research Supraphysiological Dose of Testosterone Impairs the Expression and Distribution of Sex Steroid Receptors During Endometrial Receptivity Development in Female Sprague-Dawley Rats
High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.
research Depression, Higher Level of Tension Induction, and Impaired Coping Strategies in Response to Stress in Women with PCOS Correlate with Clinical and Laboratory Indices of Hyperandrogenism and Not with Central Obesity and Insulin Resistance
Women with PCOS have more depression and stress due to high androgen levels, not obesity or insulin resistance.
research ST14 Interacts With TMEFF1 and Is a Predictor of Poor Prognosis in Ovarian Cancer
High levels of ST14 and TMEFF1 proteins in ovarian cancer are linked to worse patient outcomes and may be a new treatment target.
research C-Reactive Protein as a Novel Biomarker for Vitamin D Deficiency in Alopecia Areata
High CRP levels could indicate vitamin D deficiency in people with alopecia areata.
research The Impact of Prolactin and Vitamin D Levels as Prognostic Markers of Female Hair Loss
High prolactin and low vitamin D levels may be linked to hair loss in women.
research Systemic Subchronic Toxicity and Comparison of Four Selenium Nutritional Supplements by 90-Day Oral Exposure in Sprague-Dawley Rats
High doses of some selenium supplements caused liver and reproductive harm in rats.
research Effect of Ciclosporin on Clinical Signs of Degenerative Mucinotic Mural Folliculitis in a Young Cat
High-dose ciclosporin significantly improved a young cat's severe skin condition.
research More Cancer, Better Counting or Better at Diagnosis? The History of Skin Cancer Registration
High-quality data on skin cancer is crucial for understanding its trends and allocating healthcare resources effectively.
research Effect of Rosemary Extract on Some Internal Organs of Young Male Albino Rats: A Histological Study
High doses of rosemary extract can harm the liver, kidneys, and reproductive organs in young rats.
research Hair Cortisol: A Biomarker of Chronic Stress in Animals and Its Association With Reproduction
High levels of cortisol in hair show long-term stress which can lower fertility in animals.
research Higher Serum Ceruloplasmin Levels May Indicate the Role of Oxidative Stress in Onychomycosis
High levels of ceruloplasmin might indicate more severe toenail fungus.
research Postmenopausal Hyperandrogenism Due to Ovarian Hyperthecosis
A woman's high testosterone levels and related symptoms improved after ovary removal surgery.
research Impacts of Hyperandrogenism in Women with Polycystic Ovary Syndrome: A Literature Review
High levels of male hormones in women with PCOS can lead to fertility issues and symptoms like irregular periods, hair growth, acne, and hair loss; lifestyle changes are recommended for management.