Higher Serum Ceruloplasmin Levels May Indicate the Role of Oxidative Stress in Onychomycosis

    Funda Erduran, Funda Eren, Yıldız Hayran, Esra Fırat Oğuz, Ayşegül Yalçınkaya İyidal, Özcan Erel
    Image of study
    TLDR High levels of ceruloplasmin might indicate more severe toenail fungus.
    The study investigated the connection between oxidative stress and onychomycosis by measuring serum ceruloplasmin levels in 102 patients with the condition and 112 healthy volunteers. It found that patients with onychomycosis had significantly higher mean serum ceruloplasmin levels (866.6 U/L) compared to the control group (800.6 U/L), and these levels were positively correlated with both the duration (p=0.002, r=0.31) and severity (p<0.001, r=0.43) of the disease. The findings suggest that ceruloplasmin could serve as a potential marker for the severity and activity of onychomycosis. However, the study's limitations include its small sample size and single-center design, and the authors recommend further research with larger samples and additional biomarkers to validate these results. No conflicts of interest or financial support were reported for the study.
    Discuss this study in the Community →

    Related Community Posts Join

    1 / 1 results

    Similar Research

    5 / 80 results