Impacts of Hyperandrogenism in Women with Polycystic Ovary Syndrome: A Literature Review

December 2022 in “ International Journal of Health Science ”

Isabela Rodrigues da Silva, Shi Juin Lam, Anna Vitória de Matos Carneiro, Polyana Aparecida Bisinoto, Rubia de Souza Olivo, Adriely Portela Souza Lima, Rafael Leituga de Carvalho Cavalcante, Marina Farias Lira, Júlia Rocha Morão, Yasmim de Paula Deitos, Livia Cararo Nogueira, Neidejany de Assunção do Sacramento

hyperandrogenism polycystic ovary syndrome PCOS ovulatory disorders infertility hirsutism acne androgenic alopecia hyperinsulinemia anovulation irregular menstrual cycles androgenic hair loss male pattern baldness insulin resistance

TLDR High levels of male hormones in women with PCOS can lead to fertility issues and symptoms like irregular periods, hair growth, acne, and hair loss; lifestyle changes are recommended for management.

The literature review discusses the impacts of hyperandrogenism in women with polycystic ovary syndrome (PCOS). The review was based on 11 studies selected from 370 articles found in the Scielo and Pubmed databases. The study found that clinical manifestations of PCOS, such as ovulatory disorders, infertility, hirsutism, acne, and androgenic alopecia, are pathophysiological impacts of androgenism. Hyperinsulinemia, a condition present in women diagnosed with PCOS, contributes to androgen-dependent anovulation. Irregular menstrual cycles are indicative of anovulation, which is considered favorable for infertility associated with PCOS. The review concludes that due to the significant influence of the patient's physical conditions, therapies aimed at lifestyle changes are the first management of such a situation.

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