Health-Related Quality of Life in Women with Polycystic Ovary Syndrome Attending a Tertiary Hospital in Southeastern Spain: A Case-Control Study

    July 2020 in “ Health and Quality of Life Outcomes ”
    María Luisa Sánchez-Ferrer, Evdochia Adoamnei, María T Prieto-Sánchez, Jaime Mendiola, Shiana Corbalán-Biyang, Miriam Moñino-García, Joaquín A. Palomar-Rodríguez, Alberto M. Torres-Cantero
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    TLDR Women with Polycystic Ovary Syndrome (PCOS) have a lower health-related quality of life, especially those with an anovulatory phenotype, and may need specific interventions to improve it.
    From 2014 to 2016, a case-control study involving 117 women with Polycystic Ovary Syndrome (PCOS) and 153 controls was conducted. The study found that the health-related quality of life (HRQOL) was significantly lower in women with PCOS, especially those with an anovulatory phenotype. The Short Form-12v2 health questionnaire was used to assess HRQOL, and women with PCOS scored significantly lower in five out of eight scales. The Physical Component Summary (PCS) was also significantly lower in women with PCOS compared to controls (53.7 vs. 55.8; p = 0.01). However, no significant differences were observed for the Mental Component Summary (MCS) between women with or without PCOS or its phenotypic subtypes. The study concluded that specific interventions may be needed to improve the HRQOL in women with PCOS.
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