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Lef1 helps adult skin cells maintain their ability to heal wounds and regenerate hair, but the study's methods and conclusions have been questioned.

Hedgehog signaling in certain cells is crucial for hair growth during wound healing.

Lhx2 is a crucial regulator of the Sonic Hedgehog signaling in early mouse retinal development.

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.

The Notch signaling pathway is important for hair follicle development and could help create treatments for hair disorders.

Effective PCOS treatments require targeting specific signaling pathways.

A small group of slow-growing cells causes basal cell carcinoma to return after treatment.

The Hedgehog Signaling Pathway is important for skin and hair development and skin cancer treatment, but more research is needed to understand it fully.

SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.

The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.

β-Catenin is essential for new hair growth after skin injury.

Sinapic acid may help hair growth by activating a specific cell pathway.

Aconiti Ciliare Tuber extract may help hair grow by activating a specific cell signaling pathway.

Mice without Vitamin D receptors have hair growth problems because of issues in the hedgehog signaling pathway.

Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Targeted therapy for skin cancer is complex due to the role of the hedgehog pathway in both cancer and hair growth.

HPV genes and estradiol increase a cancer-related signaling pathway, which may be targeted for cervical cancer treatment.

Topical patidegib gel effectively treats basal cell carcinoma in Gorlin syndrome patients without causing the side effects seen with oral treatments.

The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.

Modifying certain signals in the body can help wounds heal without scars and regrow hair.

Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Hedgehog signaling in skin cells is crucial for hair growth and skin healing, but needs to be balanced to avoid harmful effects like scarring and cancer.

HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.

TDM10842, a thyroid hormone receptor activator, was found to effectively promote hair growth in mice.

Deleting MED1 in skin cells causes hair loss and skin changes.

Vitamin D receptor may help protect against UV-induced skin cancer.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.