Udenafil Induces the Hair Growth Effect of Adipose-Derived Stem Cells

July 2019 in “ Biomolecules & Therapeutics ”

Nahyun Choi, Jong Hwan Sung

Udenafil PDE5 inhibitor adipose-derived stem cells ASCs IL-4 IL12B hair growth therapeutic agent hair loss treatment

TLDR Udenafil may help hair grow by activating certain stem cells.

In 2019, researchers found that Udenafil, a PDE5 inhibitor, could potentially enhance hair growth by stimulating adipose-derived stem cells (ASCs). The study demonstrated that Udenafil increased ASC proliferation, migration, and the secretion of growth factors IL-4 and IL12B, which were found to promote hair growth. When Udenafil-treated ASCs were injected into mice, there was a significant increase in hair growth compared to untreated ASCs. The study concluded that Udenafil could potentially be used as a therapeutic agent for hair loss treatment.

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