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research The association between Interleukin (IL)-4 gene intron 3 VNTR polymorphism and alopecia areata (AA) in Turkish population

42 citations , July 2013 in “Gene”

This study found that intron 3 VNTR polymorphism in the IL-4 gene may be associated with an increased risk of alopecia areata in the Turkish population.

research Evaluation of the level of serum Interleukins (IL-2, IL-4, IL-15 andIL-17) and its relationship with disease severity in patients with alopecia areata

14 citations , July 2021 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia”

This study found that alopecia areata patients had higher baseline interleukin levels, which significantly decreased with tofacitinib treatment, though this change did not correspond to disease severity improvement.

research Physiological Doses of Red Light Induce IL‐4 Release in Cocultures between Human Keratinocytes and Immune Cells

9 citations , August 2017 in “Photochemistry and Photobiology”

This study found that isolated red light may serve as an alternative for photo-immunotherapy without additional photosensitizers, as it did not reduce keratinocyte differentiation markers or increase photo-oxidative damage, unlike treatment with IL-4 or UVA1/blue light.

research A Potential Role for IL-4 and IL-13 in an Alopecia Areata–Like Phenotype: A Clinical Perspective

4 citations , October 2020 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings”

This study suggests that IL-4 and IL-13 may play a role in the immunopathogenesis of alopecia areata in some patients, indicating a possible Th2-driven pathway in this condition.

research Adipose tissue remodeling via TSLP-mediated IL-4/IL-13 signaling: Implications for atopic dermatitis and skin barrier

June 2024 in “Journal of Allergy and Clinical Immunology”

In this study, thymic stromal lymphopoietin (TSLP) induced IL-4/IL-13 from T cells, prompting sebum secretion and adipose loss, suggesting IL-4/IL-13 may affect skin barrier function in atopic dermatitis.

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Learn

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learn Scalp Micropigmentation

How many sessions of scalp micropigmentation will I need? Most clients need 2-4 sessions of scalp micropigmentation for optimal results.
What should I avoid after scalp micropigmentation? Avoid sun exposure, swimming, sweating, and hair products after scalp micropigmentation.

learn Hair Transplant

What happens after a hair transplant? Expect mild swelling and redness, with new hair growth starting in 3 to 6 months.
Do hair transplants look natural? When done correctly, hair transplants can look completely natural and undetectable.
Is a hair transplant painful? A hair transplant is generally comfortable due to local anesthesia, with mild post-procedure soreness possible.

learn Stem Cell Factor

learn Thymosin Beta 4

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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Clinics

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Community Join

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community Il PP405 è molto promettente ma non è l'unico in grado di liberarci dalla iattura

3 upvotes 1 year ago

PP405 shows promise in hair loss treatment, but stem cell therapy using adipose-derived stem cells and ATP also successfully reversed androgenetic alopecia in mice. Stem cell therapy is costly, and some doubt the effectiveness of PP405 based on press releases.

community 4 month update to my hair regrowth journey

in Progress Pictures 74 upvotes 1 year ago

The user shared a four-month update on their hair regrowth journey using 1mg daily finasteride, 5mg daily oral minoxidil, and weekly dermarolling, noting significant improvement in hair thickness and uniform growth. They reported no side effects from minoxidil except increased hair growth on arms, fingers, and eyelashes.

community 4 month update Fin/Min/Dermatamp

28 upvotes 1 year ago

The user reported gradual hair regrowth after 4 months using oral finasteride, topical minoxidil, dermastamping, and vitamins C and D3. They noted the use of a 1.25mm dermastamp and discussed sourcing finasteride in Canada.

community Dutasteride 4.5 months really struggling what should I do

in Finasteride/Dutasteride 18 upvotes 1 year ago

The user has been on dutasteride for 4.5 months after switching from finasteride due to hair thinning, and is experiencing significant hair loss despite also using minoxidil and microneedling. Many responses suggest that dutasteride takes time to show results, often requiring patience for up to a year or more, and recommend not stopping finasteride abruptly to avoid shedding.

community 4 months!! We making progress!!

506 upvotes 1 year ago

A user shared their successful hair regrowth journey using 0.5 mg Dutasteride, 2.5 mg oral Minoxidil, and Biotin gummies, after switching from Finasteride due to insomnia. They highlighted the importance of brushing the scalp for blood flow and reported significant progress in four months without side effects.

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Experts

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