This study found that GPC1 is a key regulator of angiogenesis in human dermal microvascular endothelial cells, influenced by factors secreted by keratinocytes, and may be a target for alopecia treatment research.
This health hazard evaluation by NIOSH identified problems with ventilation and environmental control at a resort spa, potentially contributing to reported employee health complaints.
May 2018 in “Journal of Saidu Medical College Swat” The study observed that among Afghan women attending a gynecology outpatient department, the majority of those with hirsutism exhibited associated gynecological issues and were primarily categorized as having idiopathic causes or Polycystic Ovarian Disease.
205 citations
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March 2012 in “Science Translational Medicine” PGD2 stops hair growth and is higher in bald men with AGA.
April 2025 in “Antioxidants” In this study, the researchers found that the water-soluble fraction of Rhus semialata gall extract and its component Penta-O-Galloyl-β-D-Glucose promoted hair growth in human dermal papilla cells, and clinical trials supported these findings, showing improved hair density and appearance compared to placebo.
24 citations
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November 1997 in “Journal of Biological Chemistry” This study found that genes encoding mouse high-glycine/tyrosine proteins show distinct spatial and temporal expression patterns in hair follicles, suggesting diverse protein distribution during hair growth cycles.
10 citations
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January 2004 in “Dermatologic Surgery” This study found that storing hair follicle micrografts in HEPES-buffered DMEM with ACD inhibitors like aminoguanidine significantly increased hair shaft elongation compared to phosphate-buffered salt solution, suggesting improved viability for transplantation.
January 2026 in “Journal of Clinical Case Studies” This article discusses the potential of copper tripeptide (GHK-Cu) to support collagen synthesis and antioxidant activity in the context of androgenetic alopecia but reports no clinical results.
1 citations
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June 2022 in “Gene reports” This study analyzed gene expression in Pashmina goats and identified key biological processes and molecular functions involved in long-fibre production, suggesting potential pathways for enhancing this trait in other goat breeds.
April 2018 in “Radiotherapy and Oncology” Prostaglandin helps regenerate hair follicles after radiation damage.
8 citations
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March 2023 in “Journal of Clinical Epidemiology” This updated guidance from the GRADE working group addresses issues with assessing inconsistency in treatment effect estimates and evaluating the credibility of effect modifiers in systematic reviews.
November 2020 in “Journal of the American Academy of Dermatology” Intense pulsed light with radiofrequency showed mixed results in improving quality of life for hidradenitis suppurativa patients, with no clinical improvements.
April 2015 in “Andrology” This special issue contains abstracts from the ASA 40th Annual Meeting, providing an overview of various studies without reporting new primary results.
2 citations
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September 2002 in “Journal of Endocrinological Investigation” The GH-IGF-I axis is likely involved in the hormonal imbalances seen in non-obese women with functional hyperandrogenism.
This study suggests that human hair keratin-based gradient hydrogels incorporating silver ions may serve as promising dermal templates for wound healing, demonstrating favorable mechanical properties, cell interaction, and antibacterial activity.
January 2020 in “Journal of St. Marianna University” This study found that human placenta extract may enhance hair growth by increasing PG-E2 and PG-F2a production while decreasing PG-D2 levels in cultured hair follicle keratinocytes.
33 citations
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December 1999 in “Journal of Investigative Dermatology Symposium Proceedings”
57 citations
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June 2021 in “Polymers” This review discusses photothermal agent hybrids in hydrogels for antibacterial action, angiogenesis, and osteogenesis in tissue engineering, but reports no new experimental findings.
126 citations
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October 1998 in “Experimental Dermatology” This review provides an overview of the hairless gene in mice and humans, discussing its structure, expression, and implications for understanding skin physiology and human disorders related to gene disruption, but it reports no new empirical findings.
This study identified goat hair keratin gHaⅠ with strong expression in the cortex of hair follicles, showing high sequence homology to sheep keratin.
This study found changes in the PGI2 pathway, especially in gene and protein expression, in diabetic mice, but did not observe PGI2-dependent vasomotor dysfunction.
10 citations
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February 2021 in “Pharmaceutics” In this study, the novel fatty acid-conjugated tetrapeptide Palmitoyl-GDPH enhanced wound healing in rats by improving re-epithelialization and collagen deposition with minimal toxicity observed at the used dosage.
April 2020 in “BMC endocrine disorders” This case report describes a 65-year-old woman with childhood-onset growth hormone deficiency who developed panhypopituitarism, including late-onset secondary hypoadrenocorticism, affecting her respiratory and renal function.
January 2024 in “Journal of Cosmetics, Dermatological Sciences and Applications” This study found that electronically-operated pneumatic injections for administering a peptide-hyaluronic acid combination were well tolerated and led to significant improvement in hair density and thickness for men with androgenic alopecia over six months, though the exact mechanism remains uncertain.
22 citations
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December 2018 in “British Journal of Clinical Pharmacology” This study found that most adverse events reported for HPV vaccines in the VAERS system were non-serious and already known, although less common events suggest the need for further examination.
June 2018 in “The Journal of Sexual Medicine” This study used high-resolution ultrasound to investigate the pathophysiology of persistent erectile dysfunction in young men who used the drug finasteride, observing differences in erectile tissue homogeneity compared to control subjects without finasteride exposure.
2 citations
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January 2009 in “Human cell culture” This article reviews the potential benefits of GHK-Cu, EAA, and water-soluble propolis for wound healing, skin tightening, and anti-aging effects, but reports no new clinical results.
11 citations
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December 2024 in “Wound Repair and Regeneration” In this study, researchers created the WRAHPS Guidelines to standardize the reporting of preclinical wound healing studies, aiming to improve transparency, enable comparative analysis, and support the development of human clinical trials for wound healing disorders.
1 citations
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August 2023 in “Journal of Dentomaxillofacial Science” This study found that freeze-dried homologous platelet-rich plasma (FD HPRP) increased osteocalcin levels in cultured osteoblasts, suggesting its potential to support bone regeneration in periodontal treatment.