Growth Hormone Deficiency with Late-Onset Hypothalamic Hypoadrenocorticism Associated with Respiratory and Renal Dysfunction: A Case Report

    April 2020 in “ BMC endocrine disorders
    Nami Kojima, Nobuyuki Koriyama, Akinori Tokito, Kazuma Ogiso, Koshi Kusumoto, Satoshi Kubo, Yoshihiko Nishio
    TLDR A woman with childhood growth hormone deficiency had multiple hormone deficiencies and developed serious lung and kidney problems later in life.
    This case report described a 65-year-old woman with childhood-onset growth hormone deficiency (GHD) who developed combined pituitary hormone deficiency (CPHD) over time, including late-onset secondary hypoadrenocorticism in her 60s, along with severe respiratory and renal dysfunction. The patient had an empty sella turcica and other risk factors for progression from isolated GHD to CPHD. Despite GH-replacement therapy, her respiratory and renal conditions did not improve, likely due to insufficient GH administration. The report highlighted the importance of lifelong endocrinological monitoring in GHD patients with risk factors for CPHD progression. The study also noted the rarity of ACTH deficiency onset in the 60s and the need for further evaluation of this phenomenon.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Does low HGH leading to hairloss?

      in Research/Science  13 upvotes 1 year ago
      The user experiencing diffuse hair loss is using various treatments including RU58841, finasteride, minoxidil with tretinoin, anti-hair loss shampoo, and microneedling, and is considering adding peptides TB500, BPC157, and GHK-Cu. They have low growth hormone levels and are questioning its impact on hair loss, while another user suggests androgenic alopecia and androgens are likely the main cause of hair loss.

      community Balding, short, small penis. What is the point of living…

      in Treatment  405 upvotes 4 years ago
      A 24 year old male struggling with the physical and mental effects of balding, being short, and having a micropenis. Suggested treatments include taking medications such as finasteride and minoxidil, lifting weights, and trying not to compare himself to others.

      community Has anyone used growth hormone combined with minoxidil?

      in General  34 upvotes 4 days ago
      The conversation discusses using minoxidil and dutasteride for hair growth, with OP considering amino acids or growth hormone for better results. Another user inquires about the effectiveness of dutasteride.

      community Balding at the age of 17 years old

      in Chat  8 upvotes 1 year ago
      A 17-year-old experiencing hair loss is using Minoxidil but is hesitant about Finasteride due to potential side effects. Others recommend Finasteride for its effectiveness and suggest alternatives like vitamins and derma rollers.

      community Anyone here in the 0% like me?

      in Finasteride/Dutasteride  44 upvotes 1 year ago
      The user has tried topical minoxidil, oral minoxidil, finasteride, RU58841, and dermapen for over a year without seeing hair regrowth and has now switched to dutasteride, planning to continue until summer. Some responses suggest that no further hair loss could be considered progress, question the visibility of hair loss, and recommend trying vitamin D.

    Similar Research

    5 / 1000+ results
      Endocrinology

      research Endocrinology

      April 2023 in “Clinical Chemistry and Laboratory Medicine”
      The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.
      COVID-19 and Hypopituitarism

      research COVID-19 and Hypopituitarism

      15 citations , August 2021 in “Reviews in endocrine and metabolic disorders”
      COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.