TLDR HPV vaccines are generally safe but need further investigation for rare side effects.
The document from January 21, 2019, analyzed the safety profile of HPV vaccines over a decade (2007-2017) using the US Vaccine Adverse Event Reporting System (VAERS). It found 55,356 reports of adverse events following immunization (AEFI) with HPV vaccines, with the majority related to Gardasil®. The most frequently reported events were dizziness and syncope, which were non-serious and listed in the vaccines' product characteristics. The study also noted potential safety signals for less frequent AEFIs like alopecia, hyperacusis, and parosmia that need further investigation. Additionally, it observed a correlation between Google® searches and AEFI reporting trends. Despite some new signals, the study concluded that HPV vaccines have a favorable risk-benefit profile, are sometimes used outside the recommended age range, and significantly reduce the risk of some cancers, reinforcing the importance of accurate vaccine safety information dissemination.
22 citations,
December 2018 in “British Journal of Clinical Pharmacology” HPV vaccines are generally safe but need further investigation for rare side effects.
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8 citations,
January 2012 in “Dermatology” The HPV vaccine may be linked to temporary hair loss in children, but the benefits outweigh the risks.
87 citations,
October 1997 in “JAMA” Some vaccines might rarely cause hair loss, more research is needed.
717 citations,
June 2010 in “Nature” Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.
701 citations,
August 2014 in “Nature medicine” Alopecia areata can be reversed by JAK inhibitors, promoting hair regrowth.
421 citations,
April 2012 in “The New England Journal of Medicine” Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.
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391 citations,
January 2010 in “Journal of The American Academy of Dermatology” Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.
295 citations,
January 2006 in “Journal of the American Academy of Dermatology” Alopecia areata, a common autoimmune hair loss condition, often runs in families.
290 citations,
December 2017 in “Journal of The American Academy of Dermatology” Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.
