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This study found that knockdown of PCAT1 inhibited hair follicle regeneration in nude mice by disrupting the miR-329/Wnt10b axis and Wnt/β-catenin signaling, highlighting PCAT1's role in promoting follicle regrowth.

This review discusses the emerging pathophysiological factors and potential new therapies for androgenetic alopecia beyond traditional treatments, but reports no new results.

This study found a significant association between the IRS-2 gene variant and an increased risk of PCOS, especially in non-obese women in the Chinese population from Taiwan.

This research highlights a hydrogel system that could significantly improve diabetic wound healing by releasing ibuprofen to both suppress inflammation and promote tissue regeneration, indicating a strong potential for future clinical use.

This study found that applying HHORSC exosomes may enhance the hair inductivity of dermal papilla cells, potentially improving treatments for hair loss.

This review highlights that biomaterial properties can be designed to modulate macrophage activity, potentially reducing foreign body responses and enhancing tissue healing in regenerative medicine.

This study found that transplanting hair follicles into human scars may remodel fibrotic tissue and reduce scarring by altering collagen structure and decreasing pro-fibrotic factors.

This study suggests that policosanol may prevent androgenetic alopecia in mice by regulating hormone levels and suppressing premature hair follicle entry into the regression phase.

This review reported that tripeptides, such as GHK and KdPT, show promise in enhancing wound healing through multiple mechanisms, including promoting cell migration, collagen deposition, and angiogenesis, while offering antimicrobial and anti-inflammatory benefits for both acute and chronic wounds.

This study developed finasteride-containing granules using a method that improved follicular targeting for androgenic alopecia and reported potential for easy industrial production.

This study reported that methanolic extracts of Capparis decidua fruits showed significant in vitro thrombolytic activity, suggesting their potential as a dietary health supplement for preventing thrombotic cardiovascular diseases.

This study presents a new method for evaluating cosmetic treatments by measuring the resistance of hair to mechanical wear, revealing differences related to hair ethnicity and treatment type.

This study found that gelatin sponges used as scaffolds in rats with deep wounds and periosteal defects enabled regeneration of diverse tissue types, including periosteum, skin, and appendages, highlighting the role of vascular niche formation.

In this study, one type of commercial culture medium supported expression of stem cell markers in hair follicle epithelial stem cells, but their differentiation potential and hair follicle-inducing ability declined over time.

This review highlights the promising role of stem cell therapy in treating resistant diseases, while also addressing the challenges in production and clinical application, emphasizing the need for standardized manufacturing and quality assurance to enhance efficacy and safety in clinical translational research.

This review discusses various treatments for noncicatricial alopecias, such as androgenetic alopecia and alopecia areata, including mesotherapy, microneedling, and platelet-rich plasma therapy, noting that outcomes vary across these procedures.

This study utilized a pigmented human epidermal equivalent model to incorporate melanocytes into the epidermis and found enhanced differentiation potential compared to conventional in vitro systems, reflecting in vivo cellular trajectories and highlighting melanocyte-to-keratinocyte communication pathways.

This review highlights novel drug delivery systems for alopecia that enhance localization in the pilosebaceous unit, reduce systemic exposure, and support sustained drug release, with a focus on optimized follicular carriers ranging from 100-300 nm for improved drug residence compared to conventional methods.

In this review, researchers discussed various novel drug delivery systems, including lipid nanocarriers and polymeric nanoparticles, that may enhance treatment for alopecia by improving drug localization in hair follicles and reducing systemic exposure, potentially offering better outcomes than conventional treatments.

This review found that 3D bioprinting significantly advances skin tissue engineering by enabling the creation of complex, patient-specific skin structures, though technological and regulatory challenges persist, particularly in areas like scalability and physiological mimicry.

This review outlines recent advancements in understanding how micro-RNAs (miRNAs) influence hair regeneration, highlighting their role in stimulating hair growth and potential therapeutic approaches, while also addressing the challenges of clinical translation due to miRNAs' complex roles and delivery issues.

This review synthesizes both traditional and emerging molecular mechanisms of tissue remodeling across different organs, aiming to establish a theoretical basis for precision interventions in pathological conditions, according to the authors.

This review discusses recent advancements in hair follicle organoid technology for alopecia treatment but presents no new experimental results, emphasizing the potential for clinical applications and drug screening.

This study found that restoring the skin microbiome significantly improved hair growth and skin condition in androgenic alopecia model mice by modulating the immune-inflammatory balance, highlighting the potential of bacterial-based therapies for hair loss.

This review discusses the multifaceted roles of regulatory T cells in cutaneous wound healing and highlights potential therapeutic strategies targeting these cells to enhance wound repair in chronic and diabetic wounds, but reports no new clinical results.

In this study, researchers found that sesamin, a component of sesamum, modulated the AR-MAPK-Wnt signaling pathway in DHT-stimulated HaCaT keratinocytes, demonstrating potential multi-target activity against molecular events in androgenetic alopecia.

In this study, researchers observed that DHEA-induced PCOS rats experienced significant changes in gut microbiota and metabolic profiles, particularly affecting steroid and lipid metabolism, suggesting the gut-ovary axis may play a role in the pathogenesis of PCOS.

In this study, a nanoemulsion containing lavender, peppermint, and rosemary essential oils was developed and shown to promote hair growth in mice at a rate comparable to 2% topical minoxidil, suggesting a promising natural alternative due to its antioxidant and anti-inflammatory effects.

In this study, researchers used 3D bioprinting with skin stem cells and specific hydrogels to create artificial skin that successfully promoted complete wound healing and the regeneration of skin structures, including hair follicles and blood vessels, in mice.

This study found that rhamnose can restore hair-inducing gene expression in dermal papilla cells and accelerate hair follicle regeneration by promoting the hair cycle into the anagen phase, suggesting its potential therapeutic application for alopecia treatment.