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This review discusses the advantages and progress of chitosan hydrogels in vascular regeneration for tissue engineering scaffolds, highlighting modifications to enhance their application and exploring future prospects.

This review discusses emerging cancer treatment methods focusing on cellular mechanisms unique to cancer cells and concludes no new clinical results.

This review discusses the potential of regenerative medicine for chronic and neuro-degenerative pain conditions and reports no new clinical results; the authors note that further trials are needed to confirm its efficacy.

This review examines nanozymes as promising tools for cancer diagnosis and therapy due to their enzyme-mimicking catalytic properties and highlights their challenges, including biosafety and clinical translation, alongside potential improvements through biomimetic designs, particularly utilizing exosome-based strategies for targeted delivery to tumors.

This review discusses the potential of mesenchymal stem cells and their secretome, mainly extracellular vesicles, in Parkinson's disease therapy, highlighting their neuroprotective abilities and therapeutic prospects, but it reports no clinical results.

This review concluded that non-surgical hair restoration methods, such as pharmacologic and regenerative therapies, are important for delaying or supplementing surgical treatments when used properly.

This study found that both buffy coat and apheresis PRP are effective for treating androgenetic alopecia, with buffy coat PRP associated with higher patient-reported improvement despite lower platelet counts.

This review highlights icariin’s potential to regulate macrophages in varying conditions, discussing its effects on macrophage polarization, metabolism, and disease mechanisms, and noting the development of delivery systems to enhance its therapeutic impact.

This review suggests that extracellular vesicles and conditioned media might be safe and effective for skin rejuvenation and lightening, but further high-quality studies are needed to confirm these findings.

In this review, researchers discuss the role of epigenetic modifications in epidermal stem cells' decline during skin aging and identify potential interventions targeting these disruptions, suggesting significant possibilities for antiaging strategies and dermatological treatments.

This review explores the potential of regenerative cosmetics, specifically engineered skin tissues, for rejuvenating aging skin, healing wounds, and restoring hair, offering promising alternatives to traditional dermocosmetic treatments by promoting collagen production, reducing wrinkles, and regenerating hair follicles.

Ashwagandha-derived nanoparticles can promote human hair growth.

This paper reviews the role of miRNAs in stem cell therapies and hair follicle growth, reporting no new findings but highlighting recent insights into fertility treatment and wound healing.

Inflammasome proteins can indicate the severity and treatment response of various diseases and injuries.

The authors concluded that dermal white adipose tissue, influenced by factors like light irradiation, plays a significant role in modulating hair follicle cycles and could be targeted for hair growth treatments.

This review discusses platelet-rich plasma and cell-based therapies for hair loss, noting promising results but emphasizing the need for standardization and robust trials to confirm their efficacy.

In this study, researchers analyzed 355 clinical trials from ClinicalTrials.gov, initiated by the end of 2025, to provide insights into the use of extracellular vesicles as circulating biomarkers or therapeutic interventions, highlighting current research priorities and future trends.

This study found that high-concentration cell-free adipose extract effectively reduced collagen deposition and blood vessel formation in a rabbit ear model, showing promise for preventing and treating hypertrophic scars.

This study reports that extracellular microvesicles isolated from stimulated dermal fibroblasts enhanced hair follicle growth ex vivo and identified norrin as a novel modulator in hair regeneration processes.

Transethosomes improve drug delivery through the skin and show promise for treating various conditions.

This study found that hMSC secretomes from umbilical cord Wharton's jelly had the most potent angiogenic effects, whereas those from adipose tissue demonstrated the weakest angiogenic potential.

This study found that treatment with mesenchymal stem cell extracellular vesicles enhanced hair growth in mice and stimulated dermal papilla cell activity and growth factor production in vitro.

This review highlights the potential of extracellular vesicle-based therapies for treating various diseases, but it also notes challenges like the lack of regulatory guidelines that hinder their clinical development.

This study found that gelatin microspheres delivering adipose-derived stem cells significantly accelerated diabetic wound healing in rats, suggesting a promising approach for enhancing cell-based therapies.

This review discusses the potential of cell-derived nanovesicles as innovative treatment strategies for hair growth and provides no new clinical results; the authors emphasize the need for further understanding of their mechanisms.

This study found that extracellular vesicles derived from mesenchymal stem cells and umbilical cord blood plasma enhanced wound healing and reduced scar formation in mice, suggesting their potential as therapeutic agents for skin repair.

This study suggests that StemMACS MSC Expansion Media is more suitable than PowerStem MSC1 media for expanding therapeutic adipose-derived mesenchymal stem cells, with less expression of negative markers and better chromosomal stability.

This study developed a composite hydrogel that delivered multiple proteins, enhancing skin wound healing by accelerating closure and promoting hair follicle regeneration.

This review suggests that mesenchymal stem cells' therapeutic effects might be due to bioactive substances they release, rather than the cells themselves, highlighting the potential of the MSC secretome as a novel, cell-free therapeutic approach.

This case series observed that the combination of platelet-rich plasma and fat grafting improved hair quality and density in patients with non-scarring alopecia, with effects visible by 12 weeks and sustained up to one year.