Extracellular Vesicle-Based Drug Overview: Research Landscape, Quality Control, and Nonclinical Evaluation Strategies

    August 2025 in “ Signal Transduction and Targeted Therapy ”
    Gangling Xu, Jing Jin, Zhihao Fu … Junzhi Wang
    Studysummary This review highlights the potential of extracellular vesicle-based therapies for treating various diseases, but it also notes challenges like the lack of regulatory guidelines that hinder their clinical development.
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    Research cited in this study 3

    1. Extracellular Vesicles as Human Therapeutics: A Scoping Review of the Literature Journal of Extracellular Vesicles · 2024
    2. Engineered Exosomes and Composite Biomaterials for Tissue Regeneration Theranostics · 2024
    3. Biomaterials Functionalized with MSC Secreted Extracellular Vesicles and Soluble Factors for Tissue Regeneration Advanced functional materials · 2020