16 citations
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April 1978 in “Genetics Research” This study found that asebic mice exhibit abnormal sebaceous gland differentiation and insufficient sebum production due to defective regulation of cell processes, despite possessing normally developing sebaceous glands initially.
46 citations
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April 1982 in “Journal of the American Academy of Dermatology” This study found that subcutaneous isotretinoin in male hamsters reduced sebaceous gland size without affecting other androgen-dependent skin structures, while etretinate had no effect.
January 2025 in “Indian Journal of Unani Medicine” This case study observed that hijāmah bil shart (wet cupping) led to significant improvements in hair texture, reduced shedding, and overall scalp health in a 34-year-old male with androgenetic alopecia, with no adverse effects.
42 citations
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July 2014 in “Journal of biological chemistry/The Journal of biological chemistry” This study suggests that heparan sulfate is crucial for regulating hair follicle formation, cycling, and gland morphogenesis, with its ablation leading to continuous hair growth and increased gland activity in mice.
11 citations
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October 2002 in “Genetics” This study mapped a spontaneous mouse hair mutation, "hague," to keratin genes on chromosome 15 but found no gene mutations in hague mice.
40 citations
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June 2011 in “Journal of biological chemistry/The Journal of biological chemistry” This study revealed that deficiency in the enzyme FA2H in mice affected sebaceous gland function, altered sebum composition, and caused cycling alopecia, highlighting FA2H's role in hair follicle homeostasis.
January 2026 in “Scientific Reports” In this study, researchers found that sesamin, a component of sesamum, modulated the AR-MAPK-Wnt signaling pathway in DHT-stimulated HaCaT keratinocytes, demonstrating potential multi-target activity against molecular events in androgenetic alopecia.
8 citations
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May 1996 in “Endocrinology” This study found that the androgen precursors DHEA and androstenedione stimulated androgen-sensitive parameters in the sebaceous glands of the skin in castrated male hamsters.
56 citations
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September 2013 in “Experimental Dermatology” This guide reviews the biology of sebaceous glands and their evaluation methods, emphasizing their roles beyond lipid production in skin health and disease, and reports no new research results.
1 citations
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January 2022 in “Food & Function” This study found that fruit extracts from certain Egyptian Sabal species demonstrated significant anti-androgenic activity and potential therapeutic effects against benign prostatic hyperplasia in rat models and cell lines.
September 2019 in “Journal of Investigative Dermatology” This study introduced a reproducible human model using 3D-SeboSkin technology to study hidradenitis suppurativa, allowing better maintenance of skin integrity and replication of biomarker expression patterns compared to traditional skin cultures, suggesting its value for further research.
September 2017 in “Journal of Investigative Dermatology” This study suggests that the newly characterized sebocytic progenitor cells HSGC1 and HSGC2 from different skin sites may have proliferative and differentiating potential in response to DHT.
11 citations
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May 2010 in “Journal of Medicinal Chemistry” This study introduced a novel nonsteroidal androgen receptor antagonist that effectively controls sebum production in the golden Syrian hamster ear model through targeted follicular delivery.
April 2026 in “Veterinary Medicine and Science” In this case report, authors described a pet golden hamster with a confirmed adrenocortical adenocarcinoma, where laboratory testing and diagnostic imaging enabled antemortem diagnosis, despite the species' rarity for these procedures.
February 2024 in “Mağallaẗ Al-Iqtiṣād Al-Manzilī - Ǧāmiʿaẗ Al-Munūfiyyaẗ” This study reported that Egyptian and Omani men with obesity had similar nutritional and lifestyle factors contributing to their condition, highlighting the importance of diet and physical activity in managing obesity.
14 citations
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June 2005 in “PubMed” This case report describes a 57-year-old Japanese male with a folliculosebaceous cystic hamartoma containing unusual hair shaft fragments, providing insight into its characteristic histological features.
196 citations
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May 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that SZ95 sebocytes and HaCaT keratinocytes exhibit distinct enzyme expressions and activities, implicating their different roles in androgen metabolism and homeostasis in vitro.
September 2017 in “Zenodo (CERN European Organization for Nuclear Research)” This study suggests that a topical hydroalcoholic extract of liquorice root significantly reduced sebaceous gland size in Syrian hamsters, indicating potential for use in anti-acne therapy.
24 citations
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March 1996 in “Postgraduate Medical Journal” In this study, most women with hirsutism and regular menstrual cycles were diagnosed with polycystic ovary syndrome, suggesting limited use of the term 'idiopathic or racial' hirsutism without thorough evaluation.
April 2018 in “Journal of Investigative Dermatology” This study found that the absence of Hes1 in hair follicles delays secondary hair germ activation and shortens the anagen phase, impacting HFSC self-renewal and long-term hair regeneration.
June 2015 in “The American journal of dermatopathology/American journal of dermatopathology” This study demonstrated that a 1-step, peroxidase-labeled conjugated antibody method provides more accurate immunoreactivity patterns in hair follicle substructures compared to the 2-step LSAB method, which may cause false-positive staining in sebaceous glands.
1 citations
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September 2021 This study analyzed the effect of ginger hair masks and found that a significant portion of salon customers had never used them despite experiencing hair damage.
33 citations
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August 2008 in “American Journal Of Pathology” This study found that K6a expression in mouse sebaceous gland ducts correlates with Hedgehog signaling, suggesting a role in duct fate.
January 2000 in “Zhongguo yixue wulixue zazhi” This study observed that human hair keratin showed distinct morphological features depending on the dissolution speed, which could have potential applications in clinical settings for developing self-tendons.
1 citations
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January 1988 In this study, topical dehydroepiandrosterone (DHEA) doubled sebum production in women without systemic side effects, suggesting it may be a safe treatment for reduced sebum output related to menopause.
September 2019 in “Mağallaẗ al-ʿulūm al-ṭabīʿiyyaẗ wa-al-ḥayātiyyaẗ wa-al-taṭbīqiyyaẗ” This study found that camel hair from Afif has suitable physical and chemical properties for textile production and its characteristics can be enhanced with chemical additives like acetic acid.
46 citations
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August 2006 in “PubMed” In this study, researchers identified and examined males with 17 beta-HSD3 deficiency in a highly inbred Arab population, noting genetic findings and the progression of male characteristics despite being raised as females initially.
6 citations
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January 1990 in “The Journal of Dermatology” This study successfully developed a method to culture human hair follicle cells without a biological feeder layer, maintaining cell differentiation for a month.
4 citations
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February 2019 in “Journal of Cutaneous Pathology” This study suggests that the epigenetic marker 5-hmC may dynamically influence hair follicle bulge activation during anagen growth in mice, warranting further investigation into its role in stem cell regulation.