Anti-Androgenic Potential of the Fruit Extracts of Certain Egyptian Sabal Species and Their Genetic Variability Studies: A Metabolomic-Molecular Modeling Approach
January 2022
in “
Food & Function
”
anti-androgenic Sabal species fruit extracts testosterone LH FSH LC-HRMS secondary metabolites helasaoussazine pinoresinol tetra-O-caffeoylquinic acid 5-α-reductase-2 inhibitors S. blackburniana cytotoxicity BPH-1 cells genetic diversity SCoT markers CBDP markers benign prostatic hyperplasia luteinizing hormone follicle-stimulating hormone liquid chromatography-high resolution mass spectrometry 5-alpha-reductase-2 inhibitors start codon targeted markers composite banding pattern markers
TLDR Certain Egyptian Sabal fruit extracts may help treat anti-androgenic diseases like benign prostatic hyperplasia.
The study investigates the anti-androgenic potential of fruit extracts from certain Egyptian Sabal species using a metabolomic-molecular modeling approach. The research highlights the genetic variability among these species and their potential use in treating conditions like androgenic alopecia. The findings suggest that specific compounds in the fruit extracts can inhibit androgen receptors, which may help in managing hair loss. The study combines pharmacognosy, molecular genetics, and biochemistry to provide a comprehensive analysis of the therapeutic potential of these plant extracts.
