39 citations
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September 2015 in “Clinical Therapeutics” This review summarizes updated US prescribing information for teriflunomide in relapsing multiple sclerosis, highlighting its efficacy in reducing lesion activity and relapse rates but noting potential adverse effects such as headache and diarrhea.
6 citations
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November 2015 in “JAMA” This study found that oral contraceptive pills improve mild hirsutism, while flutamide and spironolactone are beneficial for more severe cases, but other therapies show inconsistent or no benefit.
April 2025 in “Pakistan Journal of Health Sciences” This study demonstrated that weekly azathioprine pulse therapy was more effective than betamethasone oral mini-pulse in promoting hair regrowth in patients with moderate to severe alopecia areata.
18 citations
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July 1998 in “Pediatric Dermatology” This study observed that pulsed doses of prednisolone resulted in excellent hair growth in 60% of young patients with widespread alopecia areata after six months, with minimal side effects.
2 citations
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January 2013 in “Iraqi journal of Medical Sciences”
July 2019 in “International journal of dermatology, venereology and leprosy sciences” This study found that oral cyclosporine was more effective than betamethasone minipulse therapy for treating Alopecia Areata, with more patients in the cyclosporine group showing excellent and good responses compared to the betamethasone group.
22 citations
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March 2019 in “European Journal of Ophthalmology” This study found that switching patients with glaucoma or ocular hypertension from benzalkonium chloride-latanoprost to preservative-free latanoprost maintained intraocular pressure control and improved tolerability, potentially enhancing treatment adherence and quality of life.
February 2024 in “Al-Azhar International Medical Journal /Al-Azhar International Medical Journal” This study concluded that topical betamethasone valerate lotion is more effective than topical 15% lactic acid solution for managing multiple patchy alopecia areata over a 12-week treatment period.
30 citations
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December 1972 in “Archives of dermatology” This report examines efforts to enhance the efficacy of topical steroids for alopecia areata using penetration-enhancing vehicles and exceptionally high concentrations, noting systemic steroids often lead to relapses and toxicity.
5 citations
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January 2014 in “Asian Journal of Chemistry” This study developed a simple and cost-effective chromatographic method for simultaneously analyzing betamethasone dipropionate and calcipotriol, achieving rapid separation within 7 minutes suitable for routine applications.
5 citations
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April 2022 in “Journal of Chromatography B” The new method can measure sleep-related hormones in hair effectively and could help track long-term sleep patterns.
July 2023 in “Journal of the ASEAN Federation of Endocrine Societies” This case study details the successful use of metyrapone to manage severe Cushing’s disease symptoms and stabilize a patient’s biochemical parameters before she underwent pituitary surgery.
87 citations
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September 2016 in “Journal of the American Academy of Dermatology” In this prospective case series, intralesional triamcinolone injections significantly reduced erythema, edema, suppuration, size, and pain in acute hidradenitis suppurativa flares, though the study's small size and design limit the findings.
This comparative clinical study found no statistically significant difference in the remission and recurrence rates between intralesional triamcinolone acetonide and methotrexate for treating localized alopecia areata, suggesting similar efficacy between the two treatments.
June 2026 in “Khyber Journal Of Medical Sciences” This study found that among adults with severe alopecia areata, alopecia totalis, or alopecia universalis, oral tofacitinib was more effective than methotrexate in reducing hair loss over a 12-week period, though long-term safety and efficacy remain unestablished.
April 2023 in “Iraqi postgraduate medical journal” This study found that combining microneedling with clobetasol propionate 0.05% cream significantly improved complete hair regrowth in alopecia areata patches compared to using the cream alone, with nearly double the rate of full hair regrowth observed in the combination treatment group.
62 citations
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December 1995 in “The Journal of Clinical Endocrinology & Metabolism” This study found that combining a GnRH agonist with a low-dose oral contraceptive was more effective in treating hirsutism than either agent alone and prevented hypoestrogenic side effects.
April 2022 in “Research Square (Research Square)” In this study, both topical clobetasol propionate and fractional Er: YAG laser followed by topical steroids demonstrated significant improvement in patients with alopecia areata, but the combined laser and steroid treatment was found to be more effective and safe.
July 2023 in “Anais Brasileiros de Dermatologia” In this study of 18 children with moderate to severe alopecia areata in Brazil, mesalazine treatment showed varied responses, with 14 patients completing evaluations and two not responding after six months, amidst treatment challenges like relocation and the COVID-19 pandemic.
January 2014 in “edoc (University of Basel)” This research suggests that fluoxymesterone, an anabolic steroid, may inhibit a key enzyme, potentially contributing to cardiovascular issues by affecting cortisol's activation of mineralocorticoid receptors.
14 citations
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March 2007 in “Pediatric pulmonology” This study found evidence suggesting that hypertrichosis may be an adverse effect of inhaled corticosteroids in children, although it does not always resolve after stopping treatment.
November 2016 in “Faridpur Medical College Journal” This study observed that Betamethasone oral mini-pulse therapy showed a good response in 60% of lichen planus patients, though further research is needed to confirm its efficacy.
30 citations
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February 2016 in “British journal of dermatology/British journal of dermatology, Supplement” This review found moderate to very low-quality evidence that spironolactone, flutamide, and cyproterone acetate combined with oral contraceptives may reduce hirsutism more effectively than placebo or metformin, though results vary among other treatments.
July 2021 in “Journal of dermatology & dermatologic surgery” In this study, two patients with severe alopecia areata who did not respond well to oral tofacitinib showed more than 50% hair regrowth after a single dose of intramuscular triamcinolone acetonide.
September 2025 in “Tạp chí Da liễu học Việt Nam” In this study, combining ablative fractional microneedle radiofrequency with oral methylprednisolone was found to enhance hair density and mature hair rates in patients with alopecia areata better than oral methylprednisolone alone, though some adverse effects and increased hair shedding were noted over time.
January 2015 in “Journal of evolution of medical and dental sciences” In this study, topical tacrolimus 0.03% cream showed good to excellent response in treating alopecia areata in 70% of participants, with no cutaneous or systemic side effects observed.
April 2024 in “Biosaintifika Journal of Biology & Biology Education” In this study, researchers observed that a topical gel containing 20% hypoxia mesenchymal stem cell secretome significantly reduced IL-15 and IFN-γ mRNA expression and baldness by 60% in male Wistar rats with fluconazole-related alopecia.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed a low-viscosity triamcinolone acetonide serum, used with a derma stamp microneedling device, to improve targeted treatment of alopecia areata, reporting favorable drug solubility, spreadability, and permeation to hair follicles, while maintaining skin safety.
5 citations
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July 2019 in “Photodiagnosis and photodynamic therapy” This study reports a case of a 59-year-old female with refractory follicular mucinosis and diffuse scalp alopecia who achieved complete clinical remission following treatment with a combination of topical tacalcitol and photodynamic therapy.
This review outlines the applications of intralesional steroid therapy, particularly triamcinolone acetonide, in several dermatological conditions and suggests further trials for certain uses but reports no new clinical findings.