The RELIEF Study: Tolerability and Efficacy of Preservative-Free Latanoprost in the Treatment of Glaucoma or Ocular Hypertension
March 2019
in “
European Journal of Ophthalmology
”
Studysummary This study found that switching patients with glaucoma or ocular hypertension from benzalkonium chloride-latanoprost to preservative-free latanoprost maintained intraocular pressure control and improved tolerability, potentially enhancing treatment adherence and quality of life. Our plain-language summary of this paper — not a Tressless recommendation.
The RELIEF study evaluated the tolerability and efficacy of preservative-free latanoprost in the treatment of glaucoma or ocular hypertension. The study found that preservative-free latanoprost was non-inferior in terms of intraocular pressure-lowering efficacy compared to benzalkonium chloride-latanoprost, with a better tolerability profile. Patients reported fewer ocular signs and symptoms, such as pain, discomfort, and dry eyes, with preservative-free latanoprost compared to benzalkonium chloride-latanoprost. The study concluded that preservative-free latanoprost may be a viable option for patients who experience adverse effects from benzalkonium chloride-preserved eye drops.
