The RELIEF Study: Tolerability and Efficacy of Preservative-Free Latanoprost in the Treatment of Glaucoma or Ocular Hypertension

    Marta Misiuk-Hojło, Maria Pomorska, Małgorzata Mulak, Marek Rękas, Joanna Wierzbowska, Marek E. Prost, Jaromir Wasyluk, Wojciech Lubiński, Karolina Podboraczyńska-Jodko, Wanda Romaniuk, Renata Kinasz, R Ortyl-Markiewicz, L Mocko, Anna Zaleska-Zmijewska, Dariusz Rokicki, Christophe Baudouin
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    TLDR Preservative-free latanoprost effectively lowers eye pressure with fewer side effects.
    The RELIEF study evaluated the tolerability and efficacy of preservative-free latanoprost in the treatment of glaucoma or ocular hypertension. The study found that preservative-free latanoprost was non-inferior in terms of intraocular pressure-lowering efficacy compared to benzalkonium chloride-latanoprost, with a better tolerability profile. Patients reported fewer ocular signs and symptoms, such as pain, discomfort, and dry eyes, with preservative-free latanoprost compared to benzalkonium chloride-latanoprost. The study concluded that preservative-free latanoprost may be a viable option for patients who experience adverse effects from benzalkonium chloride-preserved eye drops.
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