January 2008 in “Linchuang pifuke zazhi” This study found that betamethasone increased tyrosinase activity and melanin content in amelanotic melanocytes from human hair follicles, suggesting a potential mechanism for glucocorticoid treatment in vitiligo.
January 2017 in “Journal of Pakistan Association of Dermatologists” This study found that scabies was the most common skin condition among children up to 15 years old at a Karachi hospital in 2005.
18 citations
,
December 2015 in “PubMed” This study found that intralesional triamcinolone was more effective than topical betamethasone for hair regrowth in patients with localized alopecia areata.
July 2022 in “SKIN The Journal of Cutaneous Medicine” This case report presents the first successful treatment of acne keloidalis nuchae with a combination of halobetasol 0.01% and tazarotene 0.045% lotion.
15 citations
,
June 1964 in “Experimental Biology and Medicine” This study found that methotrexate treatment for 15 days suppressed tuberculin hypersensitivity in Strain 2 guinea pigs without causing lymphopenic or anti-inflammatory effects.
39 citations
,
January 1980 in “Dermatology” In this study, cyproterone acetate with ethinyl estradiol effectively treated acne, hirsutism, and alopecia in women, with the highest success in acne and rare side effects similar to estrogen contraceptives.
20 citations
,
December 2016 in “Neurodegenerative disease management” This study found that teriflunomide, an oral medication taken once daily, significantly slowed disability progression in patients with relapsing multiple sclerosis, supported by positive results in two Phase III trials and supplemented by various analyses including long-term studies and patient-reported outcomes.
25 citations
,
December 2017 in “Facial Plastic Surgery” This study observed that combining high-potency steroids with pimecrolimus might effectively stabilize hairline recession in frontal fibrosing alopecia patients.
1 citations
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December 2016 in “Journal of Pakistan Association of Dermatology” In this study, iontophoresis of medroxyprogesterone acetate significantly reduced hair growth rate in women with idiopathic facial hirsutism, without affecting serum androgen levels, and was well-tolerated as a treatment option.
53 citations
,
August 2014 in “Cochrane library” This review found no evidence supporting the efficacy of methotrexate for inducing remission in active ulcerative colitis compared to placebo or active comparators.
July 2024 in “Medical alphabet” This study observed that intradermal injections of Betamethasone were more effective than topical Clobetazole for treating alopecia areata in children, while Tofacitinib showed higher efficacy in those with atopic dermatitis.
14 citations
,
January 2017 in “Annals of Dermatology” In this retrospective study, low-dose methotrexate was observed to be effective and well-tolerated in treating recalcitrant alopecia areata multiplex, achieving complete or near-complete hair regrowth in about 90% of patients despite some experiencing elevated liver enzymes and gastrointestinal discomfort.
November 2024 in “IP Indian Journal of Clinical and Experimental Dermatology” Dermoscopy is a useful tool for diagnosing and managing topical steroid dependent face.
17 citations
,
November 2009 in “Dermato-endocrinology” This study found that a series of three monthly courses of medium-dose prednisolone pulse therapy was effective and well tolerated in most patients with active, multifocal alopecia areata but not in those with totalis/universalis.
9 citations
,
December 1958 in “Journal of Investigative Dermatology” 9α-21-difluoro-21-desoxyhydrocortisone is the most effective at stopping hair growth in rats.
11 citations
,
April 2020 in “Journal of Dermatological Treatment” This study found that combining oral isotretinoin with topical treatments was more effective than topical treatments alone for improving frontal fibrosing alopecia symptoms, despite some side effects.
2 citations
,
October 2021 in “QJM” This study found that both CO2 laser combined with topical methotrexate and calcipotriol plus betamethasone treatments improved nail psoriasis similarly, but some symptoms showed no improvement.
This study found that mycophenolate mofetil was well tolerated and effective as a second-line treatment for autoimmune hepatitis in patients who were intolerant to azathioprine.
44 citations
,
August 2014 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This study found that methotrexate may be an effective and safe treatment option for severe alopecia areata, with better regrowth results when combined with corticosteroids.
September 2024 in “Egyptian Journal of Dermatology and Venerology” This study found that intralesional injection of triamcinolone acetonide combined with latanoprost (a PGF2α analog) was more effective in treating localized alopecia areata, showing higher treatment response rates and greater reduction in severity scores compared to other treatments.
10 citations
,
April 2020 in “Dermatology and therapy” In this study of 35 patients with scalp alopecia areata, calcipotriol ointment led to faster and greater hair regrowth than clobetasol, though differences were not statistically significant.
4 citations
,
December 2023 in “Frontiers in Pharmacology” This study found that topical metformin was as effective as triple combination cream in reducing melasma severity, with minimal adverse events.
August 2026 in “Revista Medicina Cutánea Ibero-Latino-Americana” This review concludes that methotrexate remains an effective and safe first-line treatment for various inflammatory and immune-mediated skin conditions in children, despite the rise of biologic therapies.
22 citations
,
June 2017 in “Journal of dermatological treatment” This case series observed that 57% of pediatric patients with alopecia areata experienced significant hair regrowth with methotrexate treatment, which was generally safe, although some results were inconclusive due to follow-up issues.
22 citations
,
May 2017 in “Journal of dermatological treatment” This study found that BD 1/4 dilution was the most effective corticosteroid concentration for intralesional injection to treat localized alopecia areata in adults, with fewer adverse effects than TA.
August 2025 in “Skin Appendage Disorders” This study reported that the combination of tacrolimus, clobetasol, and minoxidil improved hair measurements and stabilized inflammation in primary cicatricial alopecia patients, with most tolerating the treatment well.
5 citations
,
December 1981 in “PubMed” This study describes a case where metoprolol was associated with reversible telogen effluvium, suggesting a similar mechanism of alopecia as seen with other beta-adrenoceptor antagonists.
9 citations
,
November 1980 in “Geburtshilfe und Frauenheilkunde” In this study, prolonged intravenous Fenoterol infusion was associated with intensive hair growth in most patients, although hormonal changes typically linked to such effects were not observed.
15 citations
,
July 2010 in “Journal of Allergy and Clinical Immunology” This study found that in mouse models, the novel NF-κB inhibitor DHMEQ improved symptoms of atopic dermatitis as effectively as tacrolimus or betamethasone.
August 2017 in “International journal of research in dermatology” This study found that topical 0.05% betamethasone dipropionate was the most effective treatment for patients with patchy alopecia areata, with less than 25% hair loss, over a 12-week period, compared to other topical treatments.