Treatment of Idiopathic Facial Hirsutism with Medroxyprogesterone Acetate Iontophoresis

December 2016 in “ Journal of Pakistan Association of Dermatology ”

Muneeza Rizwan, Ahsan Hameed

medroxyprogesterone acetate iontophoresis idiopathic facial hirsutism androgen MPA

TLDR Medroxyprogesterone acetate iontophoresis safely and effectively reduces facial hair growth in women.

The study conducted at Military Hospital Rawalpindi over 2 years involved 30 women aged 18-30 with idiopathic facial hirsutism. It evaluated the safety and efficacy of medroxyprogesterone acetate (MPA) administered via iontophoresis. Participants received 1 ml of a 7.5% aqueous MPA solution applied twice weekly for 16 weeks. The treatment targeted the cheeks, with the chin as a control. Results showed a significant reduction in hair length and growth rate without affecting serum androgen levels or causing significant side effects. The study concluded that MPA iontophoresis was a safe, effective, and well-tolerated treatment for idiopathic facial hirsutism.

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Research cited in this study

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