Effect of Oral Cyproterone Acetate on Hair Density, Diameter, and Endocrine Factors in Women with Idiopathic Hirsutism

January 1980 in “ Dermatology ”

J. D. R. Peereboom‐Wynia, Jos Boekhorst

cyproterone acetate idiopathic hirsutism testosterone dehydroepiandrosterone androstenedione

TLDR Cyproterone acetate temporarily reduces hair growth in women with idiopathic hirsutism but doesn't change hormone levels.

The study investigated the effects of oral cyproterone acetate on hair density and diameter in 11 women with idiopathic hirsutism over 12 treatment cycles. Results showed a reduction in hair density and diameter on the chin and left upper leg, but these effects were not permanent after stopping the therapy. Additionally, the treatment did not significantly alter plasma levels of testosterone, dehydroepiandrosterone, and androstenedione.

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research Treatment of Hirsutism, Acne, and Alopecia with Cyproterone Acetate

39 citations , January 1980 in “Dermatology”

Cyproterone acetate was effective in treating acne, hirsutism, and alopecia with few side effects.