Comparative Study Between Intralesional Injection of Prostaglandin F2α Alone or Combined with Corticosteroids in the Treatment of Alopecia Areata

    N.W. Mikhael, Nabil Ahmed, Doaa Mohammed El Habak
    Studysummary This study found that intralesional injection of triamcinolone acetonide combined with latanoprost (a PGF2α analog) was more effective in treating localized alopecia areata, showing higher treatment response rates and greater reduction in severity scores compared to other treatments.
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    Research cited in this study 15

    1. Diagnosis And Management Of Alopecia Areata: A Saudi Expert Consensus Statement (2023) Dermatology and Therapy · 2023
    2. Alopecia Areata: An Updated Review for 2023 Journal of Cutaneous Medicine and Surgery · 2023
    3. The Efficacy of Topical Prostaglandin Analogs for Hair Loss: A Systematic Review and Meta-Analysis Frontiers in Medicine · 2023
    4. Alopecia Areata: Burden of Disease, Approach to Treatment, and Current Unmet Needs Clinical, Cosmetic and Investigational Dermatology · 2023
    5. The Effect of Latanoprost 0.005% Solution in the Management of Scalp Alopecia Areata: A Randomized Double-Blind Placebo-Controlled Trial Dermatologic Therapy · 2022
    6. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    7. A Randomized Comparative Study of the Efficacy of Topical Latanoprost Versus Topical Betamethasone Dipropionate Lotion in the Treatment of Localized Alopecia Areata Indian Journal of Dermatology, Venereology and Leprology · 2021
    8. Efficacy of Topical Latanoprost Versus Minoxidil and Betamethasone Valerate on the Treatment of Alopecia Areata Journal of Dermatological Treatment · 2017
    9. SALT II: A New Take on the Severity of Alopecia Tool for Determining Percentage Scalp Hair Loss Journal of The American Academy of Dermatology · 2016
    10. Biomarkers of Alopecia Areata Disease Activity and Response to Corticosteroid Treatment Experimental dermatology · 2015
    11. Promising Alternative Clinical Uses of Prostaglandin F2α Analogs: Beyond the Eyelashes Journal of The American Academy of Dermatology · 2015
    12. Comparative Evaluation of Intralesional Triamcinolone Acetonide Injection, Narrow Band Ultraviolet B, and Their Combination in Alopecia Areata International Journal of Trichology · 2015
    13. Intralesional Steroids for Alopecia Areata International Journal of Trichology · 2010
    14. Treatment of Persistent Alopecia Areata with Sulfasalazine International Journal of Dermatology · 2008
    15. Prostaglandin Metabolism in Human Hair Follicle Experimental Dermatology · 2007

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