Comparative Study Between Intralesional Injection of Prostaglandin F2α Alone or Combined with Corticosteroids in the Treatment of Alopecia Areata

    September 2024 in “ Egyptian Journal of Dermatology and Venerology ”
    N.W. Mikhael, Nabil Ahmed, Doaa Mohammed El Habak
    Image of study
    TLDR Combining TRA and latanoprost is most effective for treating localized alopecia areata.
    This study compared the efficacy of intralesional injections of triamcinolone acetonide (TRA), latanoprost (a prostaglandin F2α analog), and a combination of both in treating localized alopecia areata (AA) in 75 patients divided into three groups. Group B, which received the combination treatment, showed the highest response rate (76%) compared to group A (64%) and group C (40%). Severity scores significantly declined in all groups post-treatment, with group B showing the most substantial improvement. The study suggests that combining TRA and latanoprost may offer enhanced efficacy in treating localized AA.
    Discuss this study in the Community →

    Research cited in this study

    15 / 15 results

    Related Community Posts Join

    6 / 102 results

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 1 year ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

      community New & Improved Hair Growth Stack for Maximum Results

      in Treatment  4 upvotes 1 year ago
      A user shared a hair growth stack using minoxidil sulfate, valproic acid, bimatoprost, blue copper peptide, and other ingredients, emphasizing a gel-based formula for better skin tolerance. Another user suggested adding a 5-alpha-reductase inhibitor like finasteride or dutasteride for more effective long-term results.

      community Min/Fin 3 months difference - 23yo dude

      in Progress Pictures  526 upvotes 7 months ago
      A 23-year-old experienced significant hair regrowth in 3 months using a topical mixture of minoxidil 5% and finasteride 1%, with added bimatoprost. The treatment is government-subsidized, costing around $15, and the user reported no side effects.

      community Painkillers May Block Minoxidil

      in Research/Science  13 upvotes 1 year ago
      Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

      community We Need A Solution For The Inflammatory Response related To AGA

      in Research/Science  16 upvotes 1 year ago
      The conversation is about finding a solution for scalp inflammation related to AGA, with the user expressing frustration that Minoxidil and Finasteride do not address inflammation. The user has researched glucocorticoids and topical NSAIDs for reducing inflammation and seeks advice from specialists.

    Related Research

    1 / 1 results