Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In a keratinocyte-specific knockout mouse model, this study found that deleting GRK2 disrupted hair follicle homeostasis, causing cyst-like structures, abnormal growth patterns, and eventual hair loss, suggesting potential links to immune-mediated alopecias.

This article discusses themes in the molecular structure of hair and reports no new research findings.

This study reveals that overexpression of Wnt3 in transgenic mouse skin leads to a short-hair phenotype and cyclical balding due to structural defects in hair shafts, highlighting a role for WNT signaling in hair growth regulation.

This study investigated the formation of a specific chemical crosslink in hair proteins and explored the role of transamidase enzymes in hair follicles.

This study found that age-related hair thinning in Caucasian women over 50 involves significant structural changes within the hair follicle, suggesting an "aged hair program" rather than just producing thinner hairs.

This review examines the histochemistry and keratinization processes of human hair, exploring the structural roles of keratin proteins, protein chains, and lipids, but offers no new results.

This review discusses the effects of protein-based cosmetics on hair properties and reports no new research findings, suggesting potential benefits for developing advanced, sustainable hair products.

This study demonstrates that spatially resolved IR and Raman imaging can effectively reveal the molecular structure and composition of untreated human hair, providing insights into its chemistry and structural integrity.

This study suggests that the outermost hair cuticle surface is rich in 18-methyleicosanic acid (18-MEA), supporting previous findings of its multilayer lipid and protein structure.

In this study, the authors concluded that a hydrolyzed eggwhite protein treatment promoted the reconnection of disulfide bonds in excessively bleached hair, after reduction and oxidation processes in permanent waving.

This study investigated the effect of peracetic acid treatment on hair fiber structure and found that disulfide bond oxidation altered thermal properties while preserving the α-crystal structure, suggesting different stabilizing interactions in hair fibers.

This study found that using a microfiber towel to dry human hair better preserves hair keratin integrity and wear resistance compared to blow-drying or using a cotton towel, as indicated by stronger alpha-helix structure in FTIR analysis.

This study used molecular dynamics simulations to model the outer surface of human hair, illustrating complex behavior and potential adsorption interactions with fatty acids, which may inform cosmetic formulation development.

This study found that human hair cuticle and cortex have different protein structures, with beta-sheet and disorder configurations in the cuticle and alpha-helical structures in the cortex.

This study concludes that SPARC is likely a secondary response during the hair cycle's transitional phases, indicating tissue-remodeling processes similar to those in wound repair, rather than initiating these transitions.

This study found that excessive heat caused the most significant structural changes in hair from Caucasian and Afro samples, especially when combined with other treatments like bleaching and straightening.

The researchers reported that keratin 33A is a structural protein specific to goat cashmere hair, with increased winter expression in high-cashmere-producing breeds.

This study found that blocking autophagy in Atg7-deficient mouse hair keratinocytes altered the molecular composition of hair shafts by increasing the abundance of proteins involved in protein turnover while keratins remained unchanged, highlighting autophagy's role in reducing non-cytoskeletal protein concentrations in hair.

In this study, researchers found that a protein-enriched cream made from Spirulina platensis improved the physical structure of natural hair, as evidenced by more intact and smoother cuticles compared to a control cream without protein, suggesting its potential for hair care applications.

In this study, reducing agents like ammonium thioglycolate, L-cysteine, and sodium sulfite in shampoo effectively decreased hair flyaway and frizz without causing damage, as no critical hair damage was observed in structural and tensile strength assessments.

This study found that bleached hair showed optimal protein structural integrity and tensile strength at pH 5, with significant changes in cross-linking, water content, and diameter at more alkaline or acidic levels.

This paper reviews the genetic aspects of hair disorders and suggests that understanding these genes could advance treatment and diagnosis; it reports no new experimental findings.

This study found that while molecular hair structures were nearly identical across individuals, genetic factors seem to influence specific lipid compositions, as seen in identical-patterned hair from parent-child pairs and identical twins, but not fraternal twins.

Lustre mutant sheep have normal hair structure and proteins but differ in felting properties.

This study analyzed the molecular evolution and functional divergence of the Dkk gene family, finding accelerated evolution in Aves and Reptilia and identifying functional differences that may impact hair follicle development via Wnt signaling inhibition.

This study developed a biobased copolymer called SELP::KP, showing improved hair strength, elasticity, and conditioning properties while being a safer alternative to conventional chemical treatments, based on application to human hair in a laboratory setting.

This article reviews methods for dissolving hair proteins and describes how solvents and molecules with hydrophobic groups interact with hair; it presents no new research findings.

This study found that treating hair with aqueous KCN converts disulfide bonds to monosulfide crosslinks, affecting the elasticity and crosslink distribution in hair microstructures.

In this study, researchers found that the naked (N) gene in mice indirectly affects the synthesis of structural proteins in mouse hair, resulting in reduced high tyrosine protein content and unusual amino acid compositions.

In this study, treatment with aqueous KCN selectively converted disulfide bonds to monosulfide crosslinks in hair, leading to changes in microstructural properties and rubberlike elasticity under specific laboratory conditions.