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    Glossary Structural Proteins

    Structural proteins are essential components of hair follicles and play a critical role in the formation and maintenance of hair. These proteins, such as keratin, provide strength, resilience, and shape to hair strands, influencing their overall health and appearance. In the context of hair loss, abnormalities or deficiencies in structural proteins can lead to weakened hair, increased shedding, and impaired growth, making them a key focus in understanding hair biology and potential treatments for hair loss.

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    1. Locations of synthesis of hair structural proteins in human anagen follicles British Journal of Dermatology · 1996 · 7 citations
    2. Characterization of Human KAP24.1, A Cuticular Hair Keratin-Associated Protein with Unusual Amino-Acid Composition and Repeat Structure 2007 · 51 citations
    3. Structural behavior of keratin-associated protein 8.1 in human hair as revealed by a monoclonal antibody Journal of Structural Biology · 2018 · 3 citations
    4. Insights into structural and proteomic alterations related to pH‐induced changes and protein deamidation in hair International Journal of Cosmetic Science · 2024
    5. Raman Microspectroscopy of Hair Cuticle With Polarized Excitation: Problem of Protein Secondary and Tertiary Structure Journal of Raman Spectroscopy · 2025
    6. Study on the skin structure, hair follicle cycle, and GSDMA protein expression in Ganxi goats Frontiers in Veterinary Science · 2025 · 1 citations
    7. Structure and hair follicle-specific expression of genes encoding the rat high sulfur protein B2 family Gene · 1998 · 12 citations
    8. Structure and expression of genes for a class of cysteine-rich proteins of the cuticle layers of differentiating wool and hair follicles. 1990 · 67 citations
    9. An investigation of the association between structural proteins and lipids with scalp hair curvature Open University of Cape Town (University of Cape Town) · 2025
    10. Human hair keratin-associated proteins: Sequence regularities and structural implications Journal of Structural Biology · 2006 · 52 citations
    11. Proteomic tools for the investigation of human hair structural proteins and evidence of weakness sites on hair keratin coil segments Analytical biochemistry · 2011 · 38 citations
    12. Effect of thermal treatments on the structural change and the hemostatic property of hair extracted proteins Colloids and surfaces. B, Biointerfaces · 2020 · 8 citations
    13. The role of keratin proteins and their genes in the growth, structure and properties of hair Birkhäuser Basel eBooks · 1997 · 228 citations
    14. Structural change of keratin protein in human hair by permanent waving treatment Polymer · 1998 · 70 citations
    15. Molecular modeling and structural characterization of a high glycine–tyrosine hair keratin associated protein 2017 · 16 citations
    16. Keratin is not only a Structural Protein in Hair: Keratin-mediated Hair Growth Research Square (Research Square) · 2020
    17. Trichohyalin: A structural protein of hair, tongue, nail, and epidermis 1993 · 27 citations
    18. Physiological roles of hair structural protein: a possible application of keratin-associated proteins to new hair growing ingredient FJ. Fragrance journal · 2007
    19. Carbonylation of hair proteins: A robust biomarker of molecular and structural oxidative damage in hair fibres International Journal of Cosmetic Science · 2025
    20. Skin Appendage Proteins of Tetrapods: Building Blocks of Claws, Feathers, Hair and Other Cornified Epithelial Structures Animals · 2025
    21. Protein chains in hair and epidermal keratin IF: Structural features and spatial arrangements Birkhäuser Basel eBooks · 1997 · 5 citations
    22. Identification of Novel Mutations in Basic Hair Keratins hHb1 and hHb6 in Monilethrix: Implications for Protein Structure and Clinical Phenotype Journal of Investigative Dermatology · 1999 · 62 citations
    23. The swelling behaviour of hair studied through the structural change of keratin protein during the permanent waving treatment Biophysical Chemistry · 2024
    24. Distinct mutations in human basic hair keratins 1 and 6 cause monilethrix: Implications for protein structure and clinical phenotype Journal of Investigative Dermatology · 1999
    25. Polymorphisms in the Human High Sulfur Hair Keratin-associated Protein 1, KAP1, Gene Family 2002 · 48 citations
    26. Hair Keratin Associated Proteins: Characterization of a Second High Sulfur KAP Gene Domain on Human Chromosome 2111In fond memory of Dr Peter Steinert. 2004 · 62 citations
    27. Human KAP Genes, Only the Half of it? Extensive Size Polymorphisms in Hair Keratin-Associated Protein Genes 2005 · 53 citations
    28. Rational design of keratin nanoparticles utilizing diverse hair protein fractions for controlled drug release Journal of the Taiwan Institute of Chemical Engineers · 2023
    29. The structure of human trichohyalin : potential multiple roles as a functional ef-hand-like calcium-binding protein, a cornified cell envelope precursor, and an intermediate filament-associated (cross-linking) protein 1993 · 2 citations
    30. Size Polymorphisms in the Human Ultrahigh Sulfur Hair Keratin-Associated Protein 4, KAP4, Gene Family 2005 · 27 citations