May 2023 in “Stem cell research & therapy” New method efficiently isolates hair growth cells from newborn mouse skin.
61 citations,
June 2014 in “Scientific Reports” Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.
July 2024 in “Frontiers in Pharmacology” Pilose antler extracts help hair growth by activating hair follicle stem cells.
9 citations,
July 2018 in “European journal of dermatology/EJD. European journal of dermatology” Disrupted sleep patterns can harm skin and hair cell renewal, but melatonin might help.
28 citations,
March 2010 in “Histochemistry and Cell Biology” Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.
57 citations,
March 2019 in “Immunity” The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
112 citations,
January 2014 in “Molecular and cellular therapies” Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
12 citations,
January 2021 in “Cell Transplantation” Baby teeth stem cells can help grow hair in mice.
72 citations,
July 2012 in “Journal of Investigative Dermatology” Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
35 citations,
January 2014 in “Journal of Tissue Engineering” Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.
235 citations,
January 2011 in “Journal of Clinical Investigation” Men with baldness due to androgenetic alopecia still have hair stem cells, but lack specific cells needed for hair growth.
36 citations,
October 2015 in “Cell reports” Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.
6 citations,
November 2020 in “Molecular and Cellular Endocrinology” Androgens reduce BMP2, which weakens the ability of certain cells to help hair stem cells become different types of cells.
5 citations,
February 2022 in “Stem cell reports” Thymic stromal lymphopoietin (TSLP) promotes hair growth, especially after skin injury.
759 citations,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
51 citations,
September 2020 in “Cell Metabolism” Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
4 citations,
November 2021 in “Frontiers in Cell and Developmental Biology” Aging causes hair loss and graying due to stem cell decline and changes in cell behavior and communication.
136 citations,
May 2019 in “Cells” Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.
1 citations,
January 2018 in “Stem cell biology and regenerative medicine” DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.
14 citations,
June 2017 in “Immunity” Special immune cells called Treg cells are important for maintaining and regenerating hair by activating a specific growth signal in hair stem cells.
9 citations,
February 2021 in “Frontiers in Cell and Developmental Biology” Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.
27 citations,
September 2018 in “Nanomedicine: Nanotechnology, Biology and Medicine” Further research is needed to improve hair regeneration using stem cells and nanomaterials.
44 citations,
September 2019 in “The EMBO Journal” Lymphatic vessels are essential for hair follicle growth and skin regeneration.
May 2023 in “Research Square (Research Square)” Shi-Bi-Man activates hair follicle stem cells and promotes hair growth by changing lactic acid metabolism and other cellular processes.
23 citations,
June 2015 in “Journal of Tissue Engineering and Regenerative Medicine” Wnt1a helps keep cells that can grow hair effective for potential hair loss treatments.
13 citations,
December 2017 in “Stem cells” Low-dose radiation affects hair stem cell function and survival by changing their genetic material's structure.
12 citations,
August 2016 in “Current opinion in genetics & development” Organs like hair follicles can renew themselves in complex ways, adapting to different needs and environments.
3 citations,
April 2019 in “Stem cells international” Markers CRABP1, Nestin, and Ephrin B2 are present in skin cancer environments and may influence their development.
18 citations,
December 2018 in “Expert Opinion on Biological Therapy” Hair follicle stem cells are promising for wound healing but require more research for safe clinical use.
10 citations,
May 2021 in “Clinical, cosmetic and investigational dermatology” UV exposure causes hair thinning, graying, and changes in hair growth cycles in mice.