research Dynamic Regulation of Retinoic Acid-Binding Proteins in Developing, Adult, and Neoplastic Skin Reveals Roles for β-Catenin and Notch Signaling
Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.
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300-330 / 1000+ resultsresearch IL-36γ Drives Skin Toxicity Induced by EGFR/MEK Inhibition and Commensal Cutibacterium Acnes
A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.
research Concise Review: Human Dermis as an Autologous Source of Stem Cells for Tissue Engineering and Regenerative Medicine
Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
research Advancing Skin Model Development: A Focus on a Self-Assembled, Induced Pluripotent Stem Cell-Derived, Xeno-Free Approach
A new ethical skin model using stem cells offers a reliable alternative for dermatological research.
research The Cellular Basis of Mechanosensory Merkel-Cell Innervation During Development
BMP signaling is essential for the development of touch domes.
research Exploring Pericyte and Cardiac Stem Cell Secretome Unveils New Tactics for Drug Discovery
New drugs for heart disease may be developed from molecules secreted by stem cells.
research Enrichment and Characterization of Human Dermal Stem/Progenitor Cells by Intracellular Granularity
Scientists identified a unique type of human skin stem cell that could help with tissue repair.
research Powder Shampoo Formulation with Antioxidant Activity: In Vitro Perspectives
The powder shampoo with cinnamon extract has strong antioxidant properties and is eco-friendly.
research To Control Site-Specific Skin Gene Expression, Autocrine Mimics Paracrine Canonical Wnt Signaling and Is Activated Ectopically in Skin Disease
The research suggests that a specific skin gene can be controlled by signals within and between cells and is wrongly activated in certain skin diseases.
research Wnt/β-Catenin Pathway in Tissue Injury: Roles in Pathology and Therapeutic Opportunities for Regeneration
The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
research Beta-Catenin Signaling Increases in Proliferating NG2+ Progenitors and Astrocytes During Post-Traumatic Gliogenesis in the Adult Brain
β-Catenin signaling is involved in brain cell growth after injury and could be a therapy target.
research Tailored Chromatin Modulation to Promote Tissue Regeneration
Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.
research States and Fates of Skin Fibroblasts Revealed Through Chromatin Accessibility
Newborn skin cells can change into wound-healing cells more easily than adult ones, which might explain why baby skin heals without scars. Understanding this could help treat chronic wounds and prevent scarring.
research Epidermal Stem Cells in Orthopedic Regenerative Medicine
Epidermal stem cells show promise for treating orthopedic injuries and diseases.
research Maintenance of Barrier Tissue Integrity by Unconventional Lymphocytes
Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.
research New-Generation Therapies for the Treatment of Hair Loss in Men
New treatments for male hair loss show promise but need more research for safety and effectiveness.
research Investigation of Transcriptional Gene Profiling in Normal Murine Hair Follicular Substructures Using Next-Generation Sequencing to Provide Potential Insights into Skin Disease
Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.
research Generation of a Laser Capture Microdissection and RNAseq-Based Human Anagen Hair Follicle Transcriptome Atlas
Scientists created a detailed map of gene activity in different parts of human hair follicles.
research Generation of Human Hair Follicle Organoids In Vitro and Ex Vivo by Co-Culture of Primary Human Hair Matrix Keratinocytes and Dermal Papilla Fibroblasts
Scientists successfully grew mini hair follicles using human skin cells, which could help treat baldness.
research Generation And Characterization Of Hair-Bearing Skin Organoids From Human Pluripotent Stem Cells
Scientists created hair-growing skin models from stem cells, which could help treat hair loss and skin diseases.
research Generation of iPS Cells from Human Hair Follicle Dermal Papilla Cells
Researchers made stem cells from human hair follicle cells with higher efficiency than from skin cells.
research Generation of Induced Pluripotent Stem Cells from Hair Follicle Bulge Neural Crest Stem Cells
Hair follicle stem cells need all reprogramming factors to become pluripotent.
research Generation of iPS-Derived Model Cells for Analyses of Hair Shaft Differentiation
Researchers created a mouse cell line to study hair growth and test hair growth drugs.
research Non-Invasive Assessment of Hair Regeneration in Androgenetic Alopecia Mice In Vivo Using Two-Photon and Second Harmonic Generation Imaging
New imaging techniques show testosterone delays hair growth and shrinks follicles in mice, but have limited depth for viewing.
research Generation of iPS-Derived Model Cells for the Analysis of Hair Development
Researchers created a cell model to study hair growth and test hair-growth drugs.
research Organogenesis From Dissociated Cells: Generation of Mature Cycling Hair Follicles From Skin-Derived Cells
Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.
research Adipose Stem Cell Exosome: Next Generation Regenerative Aesthetics and Therapeutics for Scalp and Hair
Adipose Stem Cell-derived Exosomes (ASCE) could potentially be used for hair loss treatment and scalp rejuvenation, as they have shown to increase hair length, thickness, and count, and improve conditions like androgenic alopecia and alopecia areata.
research Adipose Stem Cell Exosome: Next Generation Regenerative Aesthetics and Therapeutics for Scalp and Hair
Adipose stem cell-derived exosomes may improve hair count and scalp health, potentially outperforming current treatments like minoxidil.
research Hypoxia Improves Hair Inductivity of Dermal Papilla Cells via Nuclear NADPH Oxidase 4-Mediated Reactive Oxygen Species Generation
Low oxygen levels can make hair-growing cells better at growing hair through a process involving reactive oxygen species.
research Estetrol Prolongs Anagen in Healthy Female Scalp Hair Follicles by Positively Modulating Dermal Papilla Functions and Generation of Progenitor Stem Cells Ex Vivo
Estetrol helps keep scalp hair in the growth phase longer and improves hair follicle health by affecting the hair root and increasing stem cells.