2 citations
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February 2021 in “Case reports in dermatological medicine” In this case series, the topical botanical formulation GASHEE demonstrated significant improvements in hair regrowth without adverse events among patients with hair loss, including cases where previous treatments had failed.
April 2018 in “Journal of Investigative Dermatology” This study found that high skin expression of amphiregulin in acute graft-versus-host disease was associated with severe disease grade, poor overall survival, and increased non-relapse mortality.
1 citations
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October 2015 in “Joint bone spine” This study found that ankylosing spondylitis patients who are members of a self-help organization tend to have higher educational levels, are better informed about their disease, and have better functional outcomes than non-members, although potential confounders may affect disease outcome measures.
2 citations
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January 2005 This study found that men with vertex type androgenetic alopecia had higher triglyceride levels and lower HDL cholesterol levels compared to those with normal hair, suggesting it may be a marker of hyperlipidemia.
2 citations
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May 2017 in “International journal of pharmacy and pharmaceutical sciences/International Journal of Pharmacy and Pharmaceutical Sciences” This review discusses genetic mutations associated with Hutchinson-Gilford progeria syndrome and reports no clinical results; the authors emphasize the importance of cardiovascular monitoring in management.
January 2008 in “Journal of clinical and experimental medicine” This study reported that multiple factors including genetics and psychological influences are related to androgenetic alopecia, and finasteride showed a 77.8% response rate after three months of treatment.
12 citations
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February 2017 in “Journal of neuroscience research” This study suggests that extrasynaptic δGABA-A receptors may have a protective role in modulating the severity of catamenial-like seizures by influencing neurosteroid and benzodiazepine responses in mice.
In this study, researchers identified three novel genetic loci associated with androgenetic alopecia, including one with significant association in females only, which may indicate a role for sex-specific genetic factors in patterned hair loss.
5 citations
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July 2021 in “Endocrinology, diabetes & metabolism” This study found that glioblastoma cells express key enzymes involved in androgen synthesis, suggesting these enzymes might be potential targets for new therapeutic strategies.
17 citations
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January 2019 in “International journal of biological sciences” This study found that inserting the Tβ4 gene into cashmere goats increased cashmere yield by 74.5% without compromising quality, suggesting potential economic benefits for goat breeding.
January 2010 in “The Chinese Journal of Dermatovenereology” This study found that the prevalence of androgenetic alopecia in the Liangshan district was 15.5%, with significantly higher rates in males and Chinese Han compared to females and Chinese Yi.
March 2025 in “Chinese Medical Journal” This randomized, double-blind, placebo-controlled phase III trial found that a 24-week treatment with topical finasteride significantly increased hair growth and was well-tolerated in Chinese men with androgenetic alopecia compared to placebo.
9 citations
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January 2014 in “Molecular Genetics and Metabolism Reports” This study discovered that a specific G to C mutation in the ornithine aminotransferase gene is linked to the retarded hair growth phenotype in mice and may serve as a model for human gyrate atrophy.
13 citations
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November 2015 in “Blood Pressure” This study found that early-onset androgenetic alopecia, especially with a vertex pattern, may be an independent risk factor for cardiovascular disease and metabolic syndrome in men.
April 2025 in “Journal of Reproductive Healthcare and Medicine” This study confirmed that an injectable implant known as RISUG-PH™, when administered via the vas deferens, successfully delivers the drug Finasteride to the prostate in male rats for up to 28 days, suggesting a potential localized alternative to oral delivery methods.
3 citations
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January 2007 in “Nishinihon hifuka/Nishi Nihon hifuka” This study found that Sanguisorba Officinalis Root Extract showed potential in reducing hair loss by inhibiting FGF-5 activity, extending hair growth phases in mice and reducing hair loss in human trials.
15 citations
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December 2016 in “Advanced Pharmaceutical Bulletin” This study found that N-acetyl-glucosamine-loaded nanostructured lipid carriers showed promise for skin lightening in healthy volunteers by reducing melanin distribution.
104 citations
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October 2016 in “PLoS ONE” This study found that CRISPR/Cas9-mediated disruption of the FGF5 gene in goats increased hair follicle numbers and fiber length, suggesting more cashmere production could be achieved.
January 2024 in “Advanced Healthcare Materials” In a mouse model of androgenetic alopecia, this study developed a treatment combining a copper-curcumin nanoparticle oleogel with traditional Gua Sha therapy, which augmented hair regeneration more effectively than minoxidil by improving the follicular microenvironment and regulation of inflammatory responses.
9 citations
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July 2024 in “Internal Medicine Journal” This narrative review discusses the initiation and monitoring of gender-affirming hormone therapy in Australia, noting standard testosterone use for trans men and estradiol with anti-androgens for trans women, emphasizing the importance of monitoring cardiovascular and bone health.
2 citations
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January 2009 in “The Journal of Internal Korean Medicine” In this study, Scutellaria baicalensis was observed to reduce tissue damage and inhibit 5α-reductase expression in a rat model of benign prostatic hyperplasia.
19 citations
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January 2007 in “Biological & pharmaceutical bulletin” This study found that glycine treatment inhibited melanogenesis in B16F0 melanoma cells and reduced melanin content in C57BL/6J mice by down-regulating tyrosinase protein levels.
5 citations
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November 2017 in “Asian journal of pharmaceutical and clinical research” This study found that water fractions of Angiopteris evecta stimulated hair growth in male rabbits, suggesting potential alopecia treatment benefits pending further research in humans.
This study identified the combination of NCBP3, SDHA, and PTPRA as stable reference genes for normalizing gene expression in goat skin tissue research.
99 citations
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August 1998 in “Pain” This study found that blocking GABA(A) receptors in cat dorsal horn neurons increased evoked activity and background discharge, highlighting differences in inhibitory control systems compared to glycine receptors.
August 2015 in “Dermatologica Sinica” This study found that young adult men with moderate to severe AGA have poorer semen quality compared to those with normal to mild AGA.
578 citations
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April 1993 in “Cell” This study found that mice with a disrupted TGFα gene display a curly whisker-coat phenotype, similar to waved-1 mice, suggesting TGFα's crucial role in skin architecture and hair development.
September 1980 in “PubMed” This study found that applying a surfactant solution with 2.5% selenium disulfide to the back of guinea pigs significantly increased telogen hair, which may relate to observations of diffuse hair loss in humans under intense exposure conditions.
2 citations
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November 2024 in “PLoS ONE” This study assessed breeding value estimation methods for Korean Sapsaree dogs, finding varied accuracy across BLUP approaches and identifying significant genomic regions affecting traits like body height and hair length. The researchers suggest these findings can enhance breeding strategies for this culturally significant breed.
14 citations
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April 2015 in “Stem Cell Research & Therapy” This study found that dermal stem cells from granulation tissue promoted wound healing and reduced fibrosis in a combined radiation and skin wound mouse model.