Effects of Scutellaria Baicalensis on Prostatic Hyperplasia in Rats

    January 2009 in “ The Journal of Internal Korean Medicine ”
    김진성, 한양희, 김용성
    TLDR Scutellaria baicalensis may help treat benign prostatic hyperplasia.
    The study investigated the effects of Scutellaria baicalensis on benign prostatic hyperplasia (BPH) in a rat model. BPH is driven by dihydrotestosterone, and inhibiting 5α-reductase, which converts testosterone to dihydrotestosterone, can reduce prostate growth. In this study, Sprague-Dawley rats were used to model BPH through castration and testosterone treatment. Scutellaria baicalensis was administered and compared to finasteride, a known treatment. Results showed that Scutellaria baicalensis reduced tissue damage and inhibited 5α-reductase gene expression, suggesting it could protect glandular epithelial cells and inhibit stromal proliferation. These findings indicated that Scutellaria baicalensis might be a potential treatment for BPH.
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