52 citations,
October 2004 in “Veterinary dermatology” Melatonin and mitotane treatment led to hair re-growth in 62% of dogs with Alopecia X, but this was not always linked to normal hormone levels.
43 citations,
August 2018 in “Cell Stem Cell” Hoxc genes control hair growth through Wnt signaling.
39 citations,
October 2013 in “Plastic and Reconstructive Surgery” Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.
31 citations,
April 2016 in “Nature communications” Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.
25 citations,
July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Imiquimod cream activates hair follicle stem cells and causes early hair growth by changing immune cells and certain protein expressions.
24 citations,
May 2019 in “PLOS genetics” Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.
23 citations,
January 2021 in “Biomedicine & Pharmacotherapy” DHT stops hair regrowth in mice, similar to human hair loss.
14 citations,
April 2011 in “Cell Proliferation” Scientists can grow human hair follicle stem cells in a lab without changing their nature, which could help treat hair loss.
11 citations,
October 2017 in “International Journal of Molecular Sciences” A new drug delivery system using oil body-bound oleosin-rhFGF-10 improves wound healing and hair growth in mice.
11 citations,
January 2017 in “Evidence-based Complementary and Alternative Medicine” DA-5512 effectively improves hair growth and health, performing better than minoxidil.
11 citations,
January 2014 in “The Scientific World Journal” Cynatine HNS improves hair and nail quality in 90 days.
9 citations,
June 2021 in “Nutrients” Fisetin in fruits and vegetables helps hair growth in mice.
8 citations,
January 2015 in “Genetics and molecular research” Researchers found four key proteins that affect the development of a specific hair type in Yangtze River Delta white goats.
6 citations,
December 2021 in “PLoS Genetics” Polycomb Repressive Complex 2 is not needed for hair regeneration.
5 citations,
November 2011 in “Expert Review of Dermatology” The document concludes that early diagnosis and a comprehensive treatment plan are crucial for managing hair loss in children, with a focus on both medical and psychological support.
4 citations,
February 2020 in “Cell & tissue research/Cell and tissue research” Hair follicle stem cells might help treat traumatic brain injury.
3 citations,
January 2011 in “Wspolczesna Onkologia-Contemporary Oncology” Scalp hypothermia can prevent chemotherapy-induced hair loss but is not suitable for all patients, and more research is needed to improve prevention methods.
3 citations,
January 2005 in “Biological & Pharmaceutical Bulletin” The peptide GPIGS helps hair cells grow and speeds up hair regrowth in mice.
2 citations,
August 2020 in “Natural Product Communications” A mix of Platycladus orientalis leaf extract and alpha-terpineol helps mice grow hair by increasing growth factors and cell growth.
2 citations,
May 2015 in “PloS one” Hair follicle pores help cell survival and growth, even after radiation.
1 citations,
September 2023 in “eLife” TLR2 is important for hair growth and can be targeted to treat hair loss.
1 citations,
January 2015 in “Genetics and Molecular Research” Stopping S100A3 activity slows down hair growth in mice.
July 2024 in “Frontiers in Pharmacology” Pilose antler extracts help hair growth by activating hair follicle stem cells.
June 2024 in “Frontiers in pharmacology” 2-deoxy-D-ribose gel may help regrow hair in cases of hair loss.
February 2024 in “PloS one” Nutraceuticals that promote hair growth do not reduce tamoxifen's effectiveness in breast cancer treatment.
January 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Scientists made a mouse that shows how a specific protein in the skin changes and affects hair growth and shape.
September 2023 in “Frontiers in cell and developmental biology” Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.
March 2023 in “Clinical, cosmetic and investigational dermatology” IL-33 is linked to hair follicle damage in psoriasis and could be a treatment target for hair loss in this condition.
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.