Towards Expansion of Human Hair Follicle Stem Cells In Vitro

    April 2011 in “ Cell Proliferation ”
    Jungsu S. Oh, Parsa Mohebi, Daniel L. Farkas, Jian Tajbakhsh
    Studysummary This study demonstrates that human hair follicle stem cells can be cultured and expanded without major changes to their phenotypes, which suggests potential for use in regenerative medicine.
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    Research cited in this study 17

    1. Multipotent Nestin-Expressing Hair Follicle Stem Cells The Journal of Dermatology · 2009
    2. Multi-Potentiality of a New Immortalized Epithelial Stem Cell Line Derived from Human Hair Follicles In vitro cellular & developmental biology. Animal · 2008
    3. Multipotent Hair Follicle Stem Cells Promote Repair of Spinal Cord Injury and Recovery of Walking Function Cell Cycle · 2008
    4. Neural Potential of a Stem Cell Population in the Hair Follicle Cell Cycle · 2007
    5. Scratching the Surface of Skin Development Nature · 2007
    6. Advances in the Study of Stem-Cell-Enriched Hair Follicle Bulge Cells: A Review Featuring Characterization and Isolation of Human Bulge Cells Dermatology · 2007
    7. Isolation of a Novel Population of Multipotent Adult Stem Cells from Human Hair Follicles American Journal Of Pathology · 2006
    8. Bulge Cells of Human Hair Follicles: Segregation, Cultivation, and Properties Colloids and Surfaces B: Biointerfaces · 2006
    9. Gene Expression Profiling Gets to the Root of Human Hair Follicle Stem Cells ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 2005
    10. Characterization and Isolation of Stem Cell-Enriched Human Hair Follicle Bulge Cells ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 2005
    11. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005
    12. In Vitro Differences Between Keratinocyte Stem Cells and Transit-Amplifying Cells of the Human Hair Follicle Journal of Investigative Dermatology · 2005
    13. Multipotent Nestin-Positive, Keratin-Negative Hair-Follicle Bulge Stem Cells Can Form Neurons Proceedings of the National Academy of Sciences · 2005
    14. Enrichment for Living Murine Keratinocytes from the Hair Follicle Bulge with the Cell Surface Marker CD34 Journal of Investigative Dermatology · 2003
    15. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001
    16. Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis Cell · 2000
    17. The Biology of Hair Follicles The New England Journal of Medicine · 1999

    Related research 1

    1. Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells Journal of Clinical Investigation · 2011