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    Glossary Genetic Loci

    specific location on a chromosome for a particular gene

    A genetic locus (plural: loci) is a specific, fixed position on a chromosome where a particular gene or genetic marker is located. Think of it as an address for a gene within the vast neighborhood of the genome. This location is crucial for understanding genetic inheritance and variations, as it helps scientists pinpoint where specific traits or disorders, such as those related to alopecia, are encoded in our DNA.

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    1. GWASs Identify Genetic Loci Associated with Human Scalp Hair Whorl Direction Journal of Investigative Dermatology · 2023 · 4 citations
    2. Androgenetic alopecia: Identification of four genetic risk loci and evidence for the contribution of WNT signaling to its etiology Faculty of Health; Institute of Health and Biomedical Innovation · 2013
    3. Investigating the Genetic Association of Selected Candidate Loci with Alopecia Areata Susceptibility in Jordanian Patients Medicina · 2025 · 1 citations
    4. Investigation of the male pattern baldness major genetic susceptibility loci AR/EDA2R and 20p11 in female pattern hair loss British Journal of Dermatology · 2012 · 38 citations
    5. Androgenetic Alopecia: Identification of Four Genetic Risk Loci and Evidence for the Contribution of WNT Signaling to Its Etiology Journal of Investigative Dermatology · 2013 · 74 citations
    6. DYS459, DYS391, DYS388 and DYS19 genetic loci have high allelic frequency in patients with prostate cancer International Journal of Genetics and Molecular Biology · 2015
    7. Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria PLOS Genetics · 2018 · 308 citations
    8. A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features Nature Communications · 2016 · 196 citations
    9. Genetic prediction of male pattern baldness PLoS Genetics · 2017 · 133 citations
    10. Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability Nature Genetics · 2018 · 94 citations
    11. Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness Nature communications · 2017 · 64 citations
    12. Genetics and other factors in the aetiology of female pattern hair loss Experimental Dermatology · 2017 · 43 citations
    13. Genetic Basis of Alopecia Areata Dermatologic clinics · 2012 · 40 citations
    14. Genome-wide meta-analysis identifies novel loci conferring risk of acne vulgaris European Journal of Human Genetics · 2023 · 29 citations
    15. What does acne genetics teach us about disease pathogenesis? British Journal of Dermatology · 2019 · 29 citations
    16. Update on the Genetics of Androgenetic Alopecia, Female Pattern Hair Loss, and Alopecia Areata: Implications for Molecular Diagnostic Testing Seminars in Cutaneous Medicine and Surgery · 2012 · 11 citations
    17. Genetic Prediction of Male Pattern Baldness bioRxiv (Cold Spring Harbor Laboratory) · 2016 · 5 citations
    18. Genetic determinants of skin ageing: a systematic review and meta-analysis of genome-wide association studies and candidate genes Journal of PHYSIOLOGICAL ANTHROPOLOGY · 2025 · 3 citations
    19. Genetic prediction of male pattern baldness based on large independent datasets European Journal of Human Genetics · 2022 · 3 citations
    20. Evaluation of Susceptibility Genes/Loci Associated with Male Androgenetic Alopecia (MAGA) for Female-Pattern Hair Loss in a Chinese Han Population and a Brief Literature Review Medical Science Monitor · 2021 · 1 citations
    21. Genetic and Environmental Factors Affecting Hair Density in East Asian Populations British Journal of Dermatology · 2025
    22. GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk 2020
    23. No genetic support for a contribution of prostaglandins to the aetiology of androgenetic alopecia Faculty of Health; Institute of Health and Biomedical Innovation · 2013
    24. Molecular Genetics of Alopecias Current problems in dermatology · 2015 · 9 citations
    25. Dissection of genetic variation and evidence for pleiotropy in male pattern baldness Nature Communications · 2018 · 58 citations
    26. Genetic Insights into Acne, Androgenetic Alopecia, and Alopecia Areata: Implications for Mechanisms and Precision Dermatology Cosmetics · 2025
    27. Alopecia areata: a comprehensive review of clinical, immunologic, and genetic perspectives Discover Immunity. · 2025 · 2 citations
    28. Recent advances in the genetics of alopecia areata Medizinische Genetik · 2023
    29. Cost-effectively dissecting the genetic architecture of complex wool traits in rabbits by low-coverage sequencing Genetics selection evolution · 2022 · 5 citations
    30. Six Novel Susceptibility Loci for Early-Onset Androgenetic Alopecia and Their Unexpected Association with Common Diseases PLOS Genetics · 2012 · 87 citations