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Glossary allele

variant form of a gene at a specific chromosome location

An allele is a variant form of a gene that is located at a specific position, or locus, on a chromosome. Different alleles can result in different traits, such as hair color or susceptibility to certain conditions like alopecia. In diploid organisms, which include humans, each individual inherits two alleles for each gene, one from each parent, and the combination of these alleles determines specific characteristics.

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Research

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research Correction of Hair Shaft Defects through Allele-Specific Silencing of Mutant Krt75

6 citations , September 2015 in “Journal of Investigative Dermatology”

This study demonstrated that RNA interference targeting mutant keratin genes can effectively correct hair shaft structural defects in a mouse model by reducing mutant gene expression.

research Allelic frequencies for the seventeen Y-STR loci observed in Iraqi male patients with prostate cancer

3 citations , April 2015 in “AFRICAN JOURNAL OF BIOTECHNOLOGY”

This study found that certain Y-chromosome alleles may influence susceptibility to prostate cancer among Iraqi males, suggesting potential genetic screening markers for the disease.

research GABRA2 Alleles Moderate the Subjective Effects of Alcohol, Which are Attenuated by Finasteride

134 citations , February 2005 in “Neuropsychopharmacology”

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

research Hague (Hag): A New Mouse Hair Mutation With an Unstable Semidominant Allele

11 citations , October 2002 in “Genetics”

This study mapped a spontaneous mouse hair mutation, "hague," to keratin genes on chromosome 15 but found no gene mutations in hague mice.

Incidence of Adverse Cutaneous Drug Reactions in a Mexican Sample: An Exploratory Study on Their Association to Tumor Necrosis Factor Alpha TNF2 Allele

research Incidence of adverse cutaneous drug reactions in a Mexican sample: an exploratory study on their association to tumour necrosis factor alpha TNF2 allele

6 citations , March 2009 in “Journal of the European Academy of Dermatology and Venereology”

This study found no increased frequency of the TNF2 allele in Mexican patients with adverse cutaneous drug reactions mediated by delayed hypersensitivity, suggesting its lower relevance compared to findings in Caucasian populations.

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community 2023 study: Novel Hemp extract causes great hair (allegedly better than fin/min) growth with little to no side effects. Photos included… Thoughts?

8 upvotes 2 years ago

A novel hemp extract allegedly promotes better hair growth than minoxidil and finasteride, with minimal side effects, but the study's credibility is questioned due to potential bias and confounding factors like peppermint oil. Users express skepticism and suggest sticking with proven treatments like minoxidil and finasteride.

community Kintor (Koshine Biomedica) changed their KX-826 pictures on Amazon to a alleged study picture after backlash over fake pictures

in Product 124 upvotes 2 years ago

Kintor changed their KX-826 pictures on Amazon after backlash over fake images. Users are skeptical about the product's effectiveness and trustworthiness, with some preferring finasteride instead.

community HopeMed (Hmi115) is pissed at Absci (Abs-201)

4 upvotes 2 weeks ago

HopeMed is upset with Absci for allegedly using misleading information about HMI-115's performance compared to ABS-201. HopeMed plans to take legal action to protect its confidential data and trade secrets.

community Be very careful about the Sule clinic-Turkey

115 upvotes 3 months ago

Be cautious of Sule clinic in Turkey; they allegedly use non-doctors for hair transplants and manipulate online reviews. It's important to research thoroughly and ensure qualified professionals are involved in your treatment.

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