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Extracts from three Polynesian plants were found to promote hair growth by affecting cell growth and gene expression related to hair.

Organ transplant recipients have a higher risk of skin cancer over time, atopic dermatitis skin shows unusual bacterial and fungal patterns, a new tool for measuring hidradenitis suppurativa severity was created, and gene expression changes in male baldness suggest new treatments.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.

Activating the Sonic hedgehog gene in mice can start the hair growth phase.

Targeting hair follicles can improve skin treatments and reduce side effects.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.

Disabling the FGF5 gene in sheep leads to longer wool.

The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.

Genetic data can predict male-pattern baldness with moderate accuracy, especially for early-onset cases in some European men.

Non-coding RNAs play key roles in the hair growth cycle of Angora rabbits.

Hox genes control hair growth patterns in mammals by regulating stem cell activity in the skin.

Pea sprout extract is safe and effectively reduces hair loss.

Abnormal gene expression related to keratin causes hair loss in certain mice.

CRISPR/Cas9 gene-editing may effectively treat hair loss but requires more research for safe use.

The article concludes that understanding the molecular processes in hair follicle development can improve the quality of fibers like Angora and cashmere.

Tumor cell adhesion is linked to higher risk of SLN metastasis and melanoma recurrence, and a model including these factors predicts these outcomes better than one with just clinical data.

NCSTN gene mutation causes abnormal skin cell differentiation and more inflammation, contributing to Hidradenitis Suppurativa.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Ruxolitinib effectively regrows hair in most patients with severe hair loss.

Hair loss needs more research for better treatments.

Wnt ligands are crucial for hair growth and repair.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Transplant success has improved with better immunosuppressive drugs and donor matching.

FGF5 gene mutations cause unusually long eyelashes by affecting hair growth regulation.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.