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This study suggests that distinct chromatin topologies allow different lineage-specific enhancers to regulate Hoxd genes in mouse vibrissae and chicken feather primordia, while conserved regulatory elements maintain transcriptional robustness in the embryonic trunk across species.

This study suggests that the T allele of the SNP rs2476601 in the PTPN22 gene may increase the risk of alopecia areata, although further studies are necessary to validate this finding across different populations.

This review discusses current genomics and proteomics research on cutaneous autoimmune diseases, noting overlapping gene patterns but highlighting the scarcity of data on local gene expression in affected tissues.

This study reported that Pantaneiro sheep from the Pantanal region of Brazil exhibit greater genetic variability and adaptability compared to the commercial Texel breed, highlighting their potential for further research and importance in Brazilian sheep farming.

In this study, researchers observed significant differences in hair follicle microbiome diversity and microbial composition between hair loss and healthy groups, uncovering specific patterns and functional changes associated with female pattern hair loss, which may aid future targeted approaches for androgenetic alopecia.

CRISPR/Cas9 and prime editing can potentially fix skin disorder genes safely and effectively.

This study used whole-genome resequencing to analyze genetic diversity and selection in 17 rabbit breeds, identifying genes linked to traits like coat color and body size, which could inform breeding and conservation efforts.

This study identified novel mitochondrial DNA variations in PCOS patients from Pakistan, which may serve as genetic predisposition markers, highlighting especially the potential pathogenicity of frameshift mutations in the MT-ND2 gene.

This study found that miRNAs increase and target mRNAs and lncRNAs decrease from the anagen to telogen phase in mouse hair follicles, and these ceRNA networks may play a role in hair follicle cycling.

This study found that dermal papilla cells from different scalp regions of AGA patients showed differential gene expression related to cell proliferation, apoptosis, and signaling pathways when exposed to DHT in a 3D culture.

This research concluded that Snail2's absence in myeloid progenitors promotes tumor progression in mice, and specific zinc fingers are crucial for Snail1 and Snail2's roles in establishing epithelial-to-mesenchymal transition.

This study found that finasteride was associated with more reproductive adverse effects, including sexual dysfunction in men and fetal harm in women, compared to minoxidil in reported alopecia cases.

In this study, a herbal extract mixture significantly reduced IL-1α gene expression in HaCaT cells, suggesting it may aid in the treatment of nonscarring alopecia.

In this study, the researchers observed that Eda mRNA expression in goat skin peaks during the catagen phase of the hair cycle, suggesting its involvement in hair cycle regulation.

This study found that individuals with early onset extensive androgenetic alopecia have an elevated ratio of DHT to testosterone, but no significant genetic linkage to markers on chromosomes 2 or 5 was detected.

This review found that among emerging technologies for skin anti-aging, stem cell therapies using recipient chimerism might be more beneficial than CRISPR-Cas9 and other current innovations, though further studies on safety and efficacy are needed.

This study identified a nonsense mutation in the Sgkl gene as the cause of defective hair growth in a mutant mouse strain, implicating the SGKL signaling pathway in hair development.

This review discusses the role of the androgen receptor in breast cancer as a prognostic indicator and potential therapeutic target, highlighting its controversial therapeutic value and the need for further study.

This study used scRNA-Seq to map the transcriptional changes during zebrafish hair cell regeneration, revealing distinct phases including injury response, transient regeneration gene activation, and reactivation of developmental programs.

In this case report, a 10-month-old ethnic minority infant from Xinjiang with acrodermatitis enteropathy improved clinically and biochemically after zinc supplementation, underscoring the importance of early genetic testing for SLC39A4 mutations and individualized zinc therapy in managing this disorder.

This study identifies gene-regulatory networks related to genetic variants in skin and hair diseases, suggesting that dermal papilla cells are crucial in androgenetic alopecia.

This case report describes how personalized treatment based on Encyclopedic Tumor Analysis successfully led to durable regression in a woman with advanced pilomatrical carcinoma, unresponsive to standard care.

This study found that mutations in the FGF5 gene are the primary genetic factor causing long hair in domestic cats through an autosomal recessive mechanism.

This case report describes a 10-month-old minority infant from Xinjiang, China, with acrodermatitis enteropathy due to a SLC39A4 genetic mutation, showing clinical improvement in skin, hair, and zinc levels following zinc supplementation and highlighting the importance of early diagnosis and tailored treatment.

In this study, researchers successfully established a stable transgenic sheep fibroblast cell line containing an artificially synthesized spider dragline silk protein gene.

This study revealed that BMP5 in onychofibroblasts may play a key role in the differentiation of nail matrix keratinocytes, highlighting transcriptional similarities between nail and hair structures.

This study found that pediatric alopecia areata patients with atopic predisposition showed heightened immune and inflammatory responses, including significant immune cell infiltration, compared to adults and healthy controls.

This case report discusses a 15-year-old boy with pachyonychia congenita, identifying a keratin 17 gene mutation, and highlights the need for a national registry and more accessible genetic testing in India.

This study successfully established a transgenic sheep fibroblast cell line expressing the spider dragline silk protein gene, laying groundwork for developing transgenic sheep with this capability in hair follicles.

This study developed a stable cell line model to evaluate hair differentiation activity, offering a new tool for screening drugs that promote hair growth using mouse iPS cell-derived systems.