Mutational Analysis of Mitochondrial DNA in Maternal Inheritance of Polycystic Ovarian Syndrome

    August 2023 in “ Frontiers in Endocrinology ”
    Shaheen Bibi, Ghulam Abbas, Muhammad Zahoor Khan … Muhammad Zahoor
    Studysummary This study identified novel mitochondrial DNA variations in PCOS patients from Pakistan, which may serve as genetic predisposition markers, highlighting especially the potential pathogenicity of frameshift mutations in the MT-ND2 gene.
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    Research cited in this study 4

    1. Polycystic Ovarian Syndrome: Correlation Between Hyperandrogenism, Insulin Resistance, and Obesity Clinica Chimica Acta · 2019
    2. Polycystic Ovary Syndrome and Fertility Open Journal of Endocrine and Metabolic Diseases · 2016
    3. Polycystic Ovary Syndrome, Insulin Resistance, and Obesity: Navigating the Pathophysiologic Labyrinth International journal of reproductive medicine · 2014
    4. Polycystic Ovary Syndrome: Diagnosis and Treatment The American Journal of Medicine · 2007