A Mutation in the Serum and Glucocorticoid-Inducible Kinase-Like Kinase (SGKL) Gene Is Associated with Defective Hair Growth in Mice

    January 2004 in “ DNA Research ”
    Kentaro Masujin
    Studysummary This study identified a nonsense mutation in the Sgkl gene as the cause of defective hair growth in a mutant mouse strain, implicating the SGKL signaling pathway in hair development.
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    Research cited in this study 5

    1. Defining BMP Functions in the Hair Follicle by Conditional Ablation of BMP Receptor IA The Journal of Cell Biology · 2003
    2. The Transcriptional Repressor CDP (Cutl1) Is Essential for Epithelial Cell Differentiation of the Lung and the Hair Follicle Genes & development · 2001
    3. Multiple Roles for Activated LEF/TCF Transcription Complexes During Hair Follicle Development and Differentiation Development · 1999
    4. WNT Signaling in the Control of Hair Growth and Structure Developmental biology · 1999
    5. Mice With a Null Mutation of the TGFα Gene Have Abnormal Skin Architecture, Wavy Hair, and Curly Whiskers and Often Develop Corneal Inflammation Cell · 1993