research The Antiandrogenic Effect of Finasteride Against a Mutant Androgen Receptor
Finasteride may improve prostate cancer treatment outcomes.
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research Analysis of the FGF Gene Family Provides Insights into Aquatic Adaptation in Cetaceans
Whale genes show changes that help them live in water, like less hair and better flippers.
research Topical Mechlorethamine Restores Autoimmune-Arrested Follicular Activity in Mice with an Alopecia Areata-Like Disease by Targeting Infiltrated Lymphocytes
Mechlorethamine treatment regrew hair in mice by killing immune cells causing hair loss without harming hair follicles.
research miR-195-5p Regulates Hair Follicle Inductivity of Dermal Papilla Cells by Suppressing Wnt/β-Catenin Activation
miR-195-5p reduces hair growth ability in cells by blocking a specific growth signal.
research Cytokine Loaded Layer-By-Layer Ultrathin Matrices to Deliver Single Dermal Papilla Cells for Spot-By-Spot Hair Follicle Regeneration
Scientists have created a method to deliver specific cells that can regenerate hair follicles, potentially offering a new treatment for hair loss.
research GPR39 Marks Specific Cells Within the Sebaceous Gland and Contributes to Skin Wound Healing
GPR39 is linked to certain cells in the sebaceous gland and helps with skin healing.
research Adrenal 21-Hydroxylase Gene Mutations in Slovenian Hyperandrogenic Women: Evaluation of Corticotrophin Stimulation and HLA Polymorphisms in Screening for Carrier Status
The study concluded that testing hormone levels after stimulation is not reliable for identifying carriers of 21-hydroxylase deficiency; genetic testing is necessary.
research Hypothalamic DNA Methylation in Rats with Dihydrotestosterone-Induced Polycystic Ovary Syndrome: Effects of Low-Frequency Electro-Acupuncture
Electro-acupuncture may help treat PCOS in rats by changing brain DNA methylation.
research Vitamin D Increases Expression of Cathelicidin in Cultured Sebocytes
Vitamin D boosts a specific protein in skin cells linked to hair follicles.
research Molecular Genetics of Keratinization Disorders: What's New About Ichthyosis
Over 67 genes linked to ichthyosis help improve diagnosis and treatment.
research LncRNA-000133 from Secondary Hair Follicle of Cashmere Goat: Identification, Regulatory Network, and Its Effects on Inductive Property of Dermal Papilla Cells
A newly found RNA in Cashmere goats may play a role in hair growth and development.
research Human Macrophages Preferentially Infiltrate the Superficial Adipose Tissue
Human body's immune cells are more common in the layer of fat just beneath the skin than in deeper fat layers.
research An Investigation of Crosstalk Between Wnt/β-Catenin and Transforming Growth Factor-β Signaling in Androgenetic Alopecia
Wnt/β-catenin and TGF-β pathways affect hair loss, and activating Wnt/β-catenin could be a potential treatment.
research Study on the Zona Pellucida 4 (ZP4) Gene Sequence and Its Expression in the Ovaries of Patients with Polycystic Ovary Syndrome
The research suggests that the ZP4 gene is linked to egg development in women with PCOS but requires more study to understand its role in infertility.
research Exposure of Xenopus Laevis Tadpoles to Finasteride, an Inhibitor of 5-Alpha Reductase Activity, Impairs Spermatogenesis and Alters Hypophyseal Feedback Mechanisms
Finasteride exposure harms tadpole reproduction and hormone balance.
research The Inconsistent Regulation of HOXC13 on Different Keratins and the Regulation Mechanism on HOXC13 in Cashmere Goat (Capra Hircus)
The HOXC13 gene affects different hair proteins in cashmere goats in varied ways and is controlled by a feedback loop and other factors.
research Hair-Growth-Promoting Effect of Conditioned Medium of High Integrin α6 and Low CD71 Positive Keratinocyte Cells
A special mix from certain skin cells can help hair grow by making hair root cells grow faster and activating growth signals.
research Analysis of lncRNAs Expression Profiles in Hair Follicles of Hu Sheep Lambskin
lncRNAs may regulate hair follicle development in Hu sheep.
research 7-Phloroeckol Promotes Hair Growth on Human Follicles In Vitro
7-Phloroeckol from brown algae may help hair grow.
research Neonatal Finasteride Administration Alters Hippocampal α4 and δ GABAAR Subunits Expression and Behavioral Responses to Progesterone in Adult Rats
research Effects of Mesenchymal Stem Cell Therapy on Alopecia Areata in Cellular and Hair Follicle Organ Culture Models
Mesenchymal stem cell therapy may help treat alopecia areata by promoting hair growth and reducing inflammation.
research Effect of Ficus Carica Leaf Extract on the Gene Expression of Selected Factors in HaCaT Cells
Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.
research A Pharmacogenetic Survey of Androgen Receptor (CAG)N and (GGN)N Polymorphisms in Patients Experiencing Long-Term Side Effects After Finasteride Discontinuation
Longer CAG and GGN repeats increase alopecia risk, but no significant link to post-finasteride syndrome found.
research Micro-Current Stimulation Has Potential Effects of Hair Growth Promotion on Human Hair Follicle-Derived Papilla Cells and Animal Model
Micro-current stimulation may promote hair growth more effectively than standard treatments.
research Establishment of Keratinocyte Cell Lines from Human Hair Follicles
Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.
research Candidate SNP Markers of Reproductive Potential Predicted by Significant Change in Affinity of TATA-Binding Protein for Human Gene Promoters
Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.
research TSPO Activation Modulates the Effects of High Pressure in a Rat Ex Vivo Glaucoma Model
Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.
research A Preliminary Study of Differentially Expressed Genes in Expanded Skin and Normal Skin: Implications for Adult Skin Regeneration
The study found that expanded skin regenerates similarly to normal skin, with 77 genes playing a role in the process.
research Mrp4, A New Mitogen-Regulated Protein/Proliferin Gene; Unique in This Gene Family for Its Expression in the Adult Mouse Tail and Ear
A new gene, mrp4, is found in mice and may play a unique role in hair follicle development in tails and ears.
research MoS2 Nanoclusters-Based Biomaterials for Disease-Impaired Wound Therapy
The SA-MS hydrogel is a promising material for improving wound healing and skin regeneration in diseases like diabetes and skin cancer.