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This study reports the development of novel 4-amido-Δ4,6-steroids as potential inhibitors of 5α-reductase, showing promising in vitro results for conditions like acne and benign prostatic cancer.

This study evaluated the antiulcer potential of Glycyrrhiza glabra and found that its hydroalcoholic extract demonstrated dose-dependent protective effects against various ulcer models, comparable to standard drugs like omeprazole and cimetidine, by enhancing mucosal defenses and reducing stomach acid production.

This study found that anethole reduced oxidative stress and inflammation in acetic acid-induced colitis in mice, suggesting protective effects in this experimental setting.

This study found that mackerel fermented fish oil protected human keratinocyte cells from UVB-induced oxidative stress by scavenging free radicals and reducing cellular damage.

This study found that 4-(4-Phenoxybenzoyl)benzoic acid derivatives may act as antioxidants by scavenging certain reactive oxygen species but exhibit prooxidant behavior under specific conditions.

In this study, the researchers reported that while both propylene glycol and sodium lauryl sulfate enhanced finasteride's skin deposition, ethanol was the only effective enhancer of finasteride's permeation through the skin.

This study investigated pyranoanthocyanin Vitisin A and found it significantly lowered triglyceride levels and reduced body weight in high-fat diet-fed mice, outperforming Cyanidin-3-O-glucoside by inhibiting hepatic lipogenesis and enhancing fatty acid β-oxidation.

In this study, fractional CO2 laser treatment for alopecia areata was found to significantly increase terminal hair and patient satisfaction compared to betamethasone valerate cream alone, highlighting its efficacy and safety both as a standalone and combined treatment.

This study found that ethyl acetate extract from mangosteen pericarp exhibited the strongest antibacterial effect against Propionibacterium acnes compared to other extraction solvents.

This study aimed to enhance the skin penetration of brown algae fucoidan using a Nanostructured Lipid Carrier, achieving a formulation with good physical quality and stability.

This study used molecular dynamics simulations to illustrate the complex molecular behavior of the hair surface F-layer, highlighting how fatty acids interact with 18-MEA under different conditions.

This case report diagnosed variegate porphyria in a 33-year-old woman based on significant laboratory abnormalities, but with clinical features resembling porphyria cutanea tarda.

This study's simulations suggest that replenishing free 18‐MEA could restore damaged hair surface properties, highlighting the importance of optimal fatty acid spacing for maintaining hair integrity.

This study suggests that geranyl acetate may offer protective, anti-inflammatory, and cytoprotective effects against PPD-induced toxicity in keratinocyte cells, indicating its potential as a plant-derived treatment.

This study found that 2-ethylhexanoic acid impaired fertility in Wistar rats and delayed postnatal development of pups, suggesting potential reproductive toxicity at certain dosages.

This research focused on formulating finasteride, dutasteride, and minoxidil with cyclodextrins to enhance their solubility and skin penetration for topical use, potentially reducing scalp irritation from current alcohol-based preparations.

This study found that a combination of Ficus religiosa and Morus alba extracts promoted hair growth and Hair Follicle regeneration in a mouse model of hair loss by inducing the anagen phase and upregulating stem cell-associated genes.

This study successfully developed a synthetic route for finasteride that achieves a 30.6% yield and is suitable for industrial production, avoiding the use of expensive or poisonous reagents.

This study found that adjusting the polymer gel composition can create a more consistent release profile of finasteride with reduced initial burst release, enhancing patient compliance through in situ polymer precipitation.

This study found that several synthesized compounds were potent inhibitors of human steroid 5alpha-reductase type 2 and reduced prostate weights in treated rats, with compound 15 showing promise for potency in humans.

In this study, the researchers developed an optimal emulgel formulation for treating androgenic alopecia, determining that a base with 0.3% Carbomer Ultraz 10, 0.1% potassium sorbate, and 0.2% triethanolamine offered the best properties for drug release, application compliance, safety, and stability.

This study found that the ethanolic extract of walnut fruit diaphragm significantly improved lipid profiles, reduced oxidative stress, and had anti-inflammatory effects in hyperlipidemic rats.

This study found that a nano-cubosome formulation co-loaded with capsaicin and thiocolchicoside enhanced bioavailability and showed promising analgesic and anti-inflammatory effects in rats, potentially benefiting gout management through improved transdermal delivery.

Isotretinoin at low doses effectively treats facial papules in frontal fibrosing alopecia.

This review discusses various resveratrol derivative patents for therapeutic, nutraceutical, and cosmetic use, but reports no clinical results and notes that claims of improved efficacy lack trial evidence.

This study found that certain pyrazole derivatives may serve as effective 5α-reductase inhibitors with potential use in the treatment of androgenetic alopecia, based on molecular docking analyses.

This review discusses the pharmacological and dermatological uses of Ligustri Lucidi Fructus and its components, such as anti-inflammation, anti-allergy, anti-dermatotumor effects, and hair growth promotion, but reports no new clinical results.

This study found that compounds isolated from Osmanthus fragrans var. aurantiacus demonstrated antioxidative and anti-inflammatory activities, potentially offering therapeutic benefits for inflammatory bowel diseases by inhibiting COX-2 and iNOS enzymes and blocking ERK 1/2 MAPK signaling.

This article explores the potential applications of polyglutamic acid in cosmetics, discussing its benefits for skincare and haircare, but reports no new experimental results.

This study developed a synchronized fluorescence spectroscopic approach to quantify finasteride and tadalafil in various forms, achieving high accuracy with %recoveries of about 99.62% and 100.19% respectively, and demonstrated superior environmental friendliness compared to previous methods.