The Use of Dihydroxyacetone for Photoprotection in Variegate Porphyria
December 1999
in “
International Journal of Dermatology
”
Studysummary This case report diagnosed variegate porphyria in a 33-year-old woman based on significant laboratory abnormalities, but with clinical features resembling porphyria cutanea tarda.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
A 33-year-old woman with variegate porphyria (VP) presented with facial scarring, blisters, and skin fragility. Laboratory tests confirmed VP with elevated porphyrin levels in plasma, stool, and urine. Despite symptoms resembling porphyria cutanea tarda, the diagnosis was VP due to the lab results. The patient was advised to avoid certain medications and practice sun protection. She later used a self-tanning lotion containing dihydroxyacetone, which, combined with sunscreen, significantly reduced skin eruptions and improved her tolerance to sun exposure.
