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This study suggests that topically applied thyroid hormones T3 and T4 promote hair growth on human scalp tissues ex vivo, highlighting potential therapeutic use for hair loss conditions like androgenetic alopecia.

The study concluded that fatty acid transport protein 4 in epidermal keratinocytes is crucial for maintaining normal skin structure, as its deficiency led to hyperkeratosis and epidermal barrier disruption in mice.

In this study, prolonged intravenous Fenoterol infusion was associated with intensive hair growth in most patients, although hormonal changes typically linked to such effects were not observed.

Using finasteride with TIP extends time off period for prostate cancer patients.

In this study, cashmere goats engineered to overexpress the Tβ4 gene in hair follicles produced more cashmere, indicating that Tβ4 promotes secondary hair follicle development and enhances yield.

This review emphasizes the potential of repurposing topical L-thyroxine for skin ulcers and telogen effluvium and highlights the need for further exploration of its use in dermatology.

Topical thyroid hormones may boost hair growth.

Thyroid-stimulating hormone affects hair follicles but doesn't change hair growth or color.

In this study, 35.4% of telogen effluvium patients showed ferritin deficiency and 34.2% had vitamin D deficiency, suggesting these should be included in TE screening; TSH testing should be individualized.

This study found that both tofacitinib and methotrexate effectively reduced hair loss and psychological distress in patients with moderate-to-severe alopecia areata, but tofacitinib showed much greater efficacy. Both treatments had similar safety profiles, with no serious adverse effects reported.

In this study, patients with testicular feminization syndrome showed limited anabolic responsiveness to dihydrotestosterone, potentially due to reduced affinity of nuclear receptor sites for androgenic steroids rather than defective testosterone conversion.

Finasteride significantly reduced tics and obsessive-compulsive symptoms in Tourette syndrome patients.

This article lists the clinically important interactions and skin reactions of several drugs and substances, including THA, FK506, tamoxifen, tamsulosin, tartrazine, tea tree oil, temazepam, and temozolomide, but provides no new clinical results.

This study found that trans-3,4'-Dimethyl-3-hydroxyflavanone reduces active TGF-beta2 levels in human keratinocytes, suggesting it may enhance hair growth by suppressing the TGF-beta2 activation pathway.

This study found that intradermal injection of Secreted Frizzled-related Protein 4 inhibits, but does not block, hair follicle regeneration in mice, suggesting potential therapeutic applications for hair follicle regeneration disorders.

In this study, thymosin beta4 over-expression in transgenic mice was linked to accelerated hair growth and abnormal tooth development, suggesting roles in hair and tooth physiology.

This review highlights the role of the receptor TLR4 in cellular aging and age-related diseases, suggesting it as a potential therapeutic target due to its contribution to persistent inflammation and symptom regulation in these conditions.

This case report illustrates that high-dose biotin supplementation can cause false thyroid function test abnormalities in vitro, emphasizing the need to assess biotin intake before testing.

This study found that formalin-induced pain in rats nearly eliminates testosterone in the brain and spinal cord by likely increasing 5α-reductase activity, but normalizes serum levels after 24 hours.

This study found that finasteride significantly inhibits the metabolism of tirilazad to its active metabolites without greatly affecting tirilazad's overall clearance.

This study found that intermittent treatment with FTI lonafarnib and sulforaphane may be a promising therapeutic approach for children with Hutchinson-Gilford progeria syndrome, as it improved the cellular phenotype.

TSH influences keratin expression in human hair follicles.

This study found that testosterone therapy improved physical performance and strength in older men with low testosterone over 36 months, whether administered alone or with finasteride.

This report presents a case where female pattern hair loss might be linked to tamoxifen use, with increased androgen receptor expression observed in the affected scalp area.

This article discusses the preparation of tritium-labeled testosterone metabolites and reports no new experimental findings.

In this open-label trial, Tofacitinib was well tolerated and improved IFN and cytokine scores, as well as overall skin pathology, in individuals with Down syndrome and immune skin conditions.

This case study reports that low-dose testosterone therapy improved libido and sexual functions in a 36-year-old fragile X carrier female with hypoactive sexual desire disorder when monitored regularly for lab parameters.

This study concluded that KLF4 is a crucial regulator of hair follicle stem cell quiescence and may work by interacting with multiple transcription factors to control related genes.

The researchers in this study identified molecular mechanisms involved in frontal fibrosis alopecia, highlighting immune response and fatty acid metabolism, and developed a four-gene diagnostic model showing high accuracy in distinguishing affected individuals from controls.

This study found that the miR-140-y-TCF4 axis regulates the proliferation of goose embryonic dermal fibroblast cells by affecting the Wnt signaling pathway, highlighting its role as a dynamic regulator during skin and feather follicle development.