MiR-140-y Targets TCF4 to Regulate the Wnt Signaling Pathway and Promote Embryonic Feather Follicle Development in Hungarian White Goose

    February 2024 in “ Poultry Science ”
    Jingyun Ma, Yupu Song, Ichraf Mabrouk … Yongfeng Sun
    Studysummary This study found that the miR-140-y-TCF4 axis regulates the proliferation of goose embryonic dermal fibroblast cells by affecting the Wnt signaling pathway, highlighting its role as a dynamic regulator during skin and feather follicle development.
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    Research cited in this study 7

    1. Regulation of Feather Follicle Development and Msx2 Gene SNP Degradation in Hungarian White Goose BMC Genomics · 2022
    2. Transcriptional Characteristics Show That miR-144-y/FOXO3 Participates in Embryonic Skin and Feather Follicle Development in Zhedong White Goose Animals · 2022
    3. MiR-140-5p in Small Extracellular Vesicles From Human Papilla Cells Stimulates Hair Growth by Promoting Proliferation of Outer Root Sheath and Hair Matrix Cells Frontiers in cell and developmental biology · 2020
    4. Targeting Wnt/β-Catenin Pathway for Developing Therapies for Hair Loss International Journal of Molecular Sciences · 2020
    5. Macrophage-Derived Extracellular Vesicle Promotes Hair Growth Cells · 2020
    6. MAD2B Acts as a Negative Regulatory Partner of TCF4 on Proliferation in Human Dermal Papilla Cells Scientific Reports · 2017
    7. High-Throughput Sequencing Reveals miRNAs Affecting Follicle Development in Chicken International journal of genetics and genomics · 2017