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GlossaryTCF4

regulates gene expression crucial for nervous system development

TCF4, or Transcription Factor 4, is a protein that plays a crucial role in regulating the expression of genes involved in various biological processes, including cell growth, differentiation, and development. It is particularly important in the development of the nervous system and has been implicated in several neurological disorders.

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Twist1 Contributes to the Maintenance of Some Biological Properties of Dermal Papilla Cells In Vitro by Forming a Complex With Tcf4 and β-Catenin

research Twist1 Contributes to the Maintenance of Some Biological Properties of Dermal Papilla Cells In Vitro by Forming a Complex With Tcf4 and β-Catenin

13 citations , August 2020 in “Frontiers in Cell and Developmental Biology”

Twist1 helps maintain important features of cells crucial for hair growth by working with Tcf4 and β-catenin.

research MAD2B Acts as a Negative Regulatory Partner of TCF4 on Proliferation in Human Dermal Papilla Cells

8 citations , September 2017 in “Scientific Reports”

MAD2B slows down the growth of skin cells that are important for hair development by interacting with TCF4.

research The Association of Wnt – Factor TCF7L2 Gene Polymorphism and Treated Alopecia Areata: Platelet Rich Plasma Vs Conventional

February 2024 in “Zagazig University Medical Journal”

TCF7L2 gene polymorphism is linked to alopecia areata, but it doesn't affect the success of PRP or conventional treatments.

research In Vivo Transcriptional Governance of Hair Follicle Stem Cells by Canonical Wnt Regulators

173 citations , January 2014 in “Nature Cell Biology”

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

research Temporal Layering of Signaling Effectors Drives Chromatin Remodeling During Hair Follicle Stem Cell Lineage Progression

85 citations , January 2018 in “Cell stem cell”

Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.

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